Dbfetch
ID OW496012; SV 1; linear; genomic DNA; STD; HUM; 8682 BP. XX AC OW496012; XX PR Project:PRJEB52229; XX DT 28-APR-2022 (Rel. 144, Created) DT 29-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DRA gene for MHC class II antigen, allele DE HLA-DRA*01:01:01:NEW1 XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Turner R T.; RT ; RL Submitted (08-APR-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, The Royal Free Hospital, Pond Street, RL London, NW3 2QU, United Kingdom XX DR MD5; fd5015834bdbc63251d52c4b35eb0827. XX FH Key Location/Qualifiers FH FT source 1..8682 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="32_32" FT /db_xref="taxon:9606" FT CDS join(1449..1530,3944..4189,4681..4962,5252..5406) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH2618616.1" FT /translation="MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSG FT EFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNY FT TPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFL FT PREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL FT GLTVGLVGIIIGTIFIIKGVRKSNAAERRGPL" FT exon 1449..1530 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT intron 1531..3943 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT exon 3944..4189 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT intron 4190..4680 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT exon 4681..4962 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT intron 4963..5251 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT exon 5252..5406 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=4 XX SQ Sequence 8682 BP; 2534 A; 1810 C; 1847 G; 2491 T; 0 other; ctccctcact gccaggtcac tcttcatgga agtatttgta ttccagtcct ttctgtggaa 60 agaaattaac attctccttt tcataacact gtatcttcag aaacaagaga gtcgaagtct 120 cctaattttc aggactgtct atgttgaaca tcaaaatata ttctttagag cagatcttta 180 ataatcatat gacaagagaa aaactttcat aatcttatga catgagggaa ggaatattaa 240 agccgttctg tgggttatta tctctaacgt tcccaataga ataggctttg ccagctgggt 300 gcggtggctc atgcctgtaa tcccagcact ttgcgaggcc aaggcgggca aatcacgagg 360 tcaggagtct gagaccagcc tgaccaacat ggtgaaaccc cgtctctact aaaaatacaa 420 aaattagccg ggcatggtgg tgggcgcctg taatcccagc tactcaggag gctgaggcag 480 gagaatcgct tgaacccggg aggcggagat tacaatgagc tgagatcaca ccaccaactc 540 cagcttgggc gacagagcaa gactctgtct aaaaaaaaaa aaaaaaaaaa agaataggct 600 ttgcccacta tactctctca tattcattga cctgaatcct caaatgaggt gtgtccatta 660 gtcaactcca atctcttgtc atatataaga tggtagagat gagaagaagg tagctccttt 720 acagcccact atttccacta actactacct gtgtttcaag atacagcctt tcatccttct 780 ccagtgttga gagtgttgaa cctcagagtt tctcctctca ttttctctaa atgagataca 840 atgccagcca tcccaagctc ttggcctgag ttgatcatct tgaagtctag gactccaaga 900 agcatgaaag agcttcttta gtgaagctat gtcctcagta ctgccaaaat tcagacaatc 960 tccatggcct gacaatttac cttctatttg ggtaatttat tgtcccttac gcaaactctc 1020 caactgtcat tgcacagaca tatgatctgt atttagctct cactttaggt gtttccattg 1080 attctattct cactaatgtg cttcaggtat atccctgtct agaagtcaga ttggggttaa 1140 agagtctgtc cgtgattgac taacagtctt aaatacttga tttgttgttg ttgttgtcct 1200 gtttgtttaa gaactttact tctttatcca atgaacggag tatcttgtgt cctggaccct 1260 ttgcaagaac ccttccccta gcaacagatg cgtcatctca aaatattttt ctgattggcc 1320 aaagagtaat tgatttgcat tttaatggtc agactctatt acaccccaca ttctcttttc 1380 ttttattctt gtctgttctg cctcactccc gagctctact gactcccaaa agagcgccca 1440 agaagaaaat ggccataagt ggagtccctg tgctaggatt tttcatcata gctgtgctga 1500 tgagcgctca ggaatcatgg gctatcaaag gtaggtgctg agggaatgaa atctgggacg 1560 atagactacg aagcattgga gaaaagacct atggacattt ggaagataat gtgtggagtg 1620 aaagaatagt gtgacaggta ttatgtggtc tcgacagaaa gtataacaaa ttgtggtttg 1680 gtggagttct tccctcacca caaactgaag taagtcaaat ttggtttaga gggtcaaaac 1740 tgagttgtgt attgatgaat agcacggtcc tgctacaagc caaactgggg gtgggggtgg 1800 gggtggggga ggaagaatat tttctggcaa gcattaacaa gttatatttc tgggctttaa 1860 ttattctttc tggaaaatta gtaaaattaa aaactaaaaa ccacacatag ttttgctaga 1920 attaaatgaa aaaaaaagtt attagccctg ttcttatctg aatacatgat acagtagtta 1980 ttttttggag tgtaaatcct gtcggtatat attgagcaca tatattgtgt tgaagattac 2040 tagaaggaaa agtcatcaaa aagcaacaat ttaccccagg aaaaggggag ggaaggcatg 2100 ctgatatgag ttgcctcatg ggacagtgat agccattccc tgccttccca tctccatggt 2160 acagcagatc ttatatcatg ttaacttagt aatatttcca agagagtaga aaaataagga 2220 aggaaatggg gaatctgata ttattctctc tcatctccag agcaacattg gtgctgttgt 2280 aaagatgtac tgtagaaaag tattcttcac ccagcgtgac ccccacagaa ggtgtcaggt 2340 agacttgaaa taagcaaagt aataacccag ctcccatacc catagtggca attgtagatt 2400 tctattgccc caaaagagcc atacataggg atacttacct agaaagacag aggctcttcc 2460 cttggtttgt gaagaggcag ctagtatatt tgtgtgtgtt tgcatagatg caaacggtaa 2520 ataaattcct aggtttatca atacacagtc aaacattaaa atctctcatc ttggctgggc 2580 acggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 2640 tcaagagatc gagaccgtcc tgggcaacat ggtgaaaccc cgtctctact aaaaatacaa 2700 aaaattagct gggtatggtg gcacacgcct gtagtcccag ctactcggga ggctgaggca 2760 ggaggattgc ttgagcccgg gaggcggagg ttgcagtgag ctgagatggt gccactgcac 2820 tccagcctgg cgatagagca agactccgtc tcaaacaacc aaaccaaaac aaaacaaaat 2880 atctcacctt atctttgaag actaaggaaa aaaaaaatct cccactcatc gatacactcc 2940 acagaggcag catactctcc cagtgtagct ttctcttttc atgttcatta ttcccttggt 3000 gttggttatt ctcaatgtca atcgtaacag aacatcttcc ataataacag tcccaattta 3060 aggagcatta agataaaagg tggaattgcc aaggtcaatc cagacgagaa ccttctcata 3120 gaggtaacca ccgtgtgggt ttggatgctg ggaagcaggg ggactatgac gctacaaggt 3180 ctcagtctta atttttggag tacttcagtc cccaggtata ttttccatag atttggccct 3240 taaataaaaa gaagcttctg actctaaaat gtaaacagtg cttgttacag tcttgttgat 3300 atattaagaa attactcacc ttatctcatt taatcttaaa aacaaacccc tgacaggatc 3360 aaaaccacag cagggctaca taataggaaa actatacata aataggtaga ataatctgct 3420 caggatcact aggtaagttg ctgaataaga attcaagatg tttttgatcc cagagtttaa 3480 aacccaacct ttcaaacagt gtttccttct tcttagagta caatgttctg agaaagagat 3540 cctctggaat tctggcctaa gtgtatttaa tgcccgggta aagaaagtga gagaacattt 3600 ctctttaggg gctgctgctg gatttctaaa aagaaaataa tttctcagct agtaacatgg 3660 agccaaacaa cagcttcaca agactctggg ttctttagcc ctcatctcct tcaatccacc 3720 ctctttataa ccagtccttc ttgtttttcc cctcccagct ttgttcagca gcatgccctt 3780 cacccagacc ttgtcttgtc actcatccct actcgccatc attctttcat tcctcttggc 3840 ccaatctctc tccaccactt cctgcctaca tgtatgtagg ttattcattt ccctctcttg 3900 attcccccca cccaactctc tttctccatt tcttgccttt cagaagaaca tgtgatcatc 3960 caggccgagt tctatctgaa tcctgaccaa tcaggcgagt ttatgtttga ctttgatggt 4020 gatgagattt tccatgtgga tatggcaaag aaggagacgg tctggcggct tgaagaattt 4080 ggacgatttg ccagctttga ggctcaaggt gcattggcca acatagctgt ggacaaagcc 4140 aacctggaaa tcatgacaaa gcgctccaac tatactccga tcaccaatgg tacctccctc 4200 tctgctgcac tcctggacat gggaatccat agtttgaaag tagttgcttc agctctttgt 4260 gttagattat tgtaactgat tttccctcca agggcctaac cttgccatta acaagcccca 4320 aattctcatg ccagaggtct gagaacttta tgggtttgat cctatcttgt tgtgctcaag 4380 tcttgtctct gtcatccatg gtctcctacg aagtcattgc cctaagttca tgctagggga 4440 gccagaaggg aagtccttgg atatcttata cctcaatatt ggctcaattt cttggggagg 4500 gggtgctgtc agagattgtt atctgaggat gtgacataga tttctcaggg cacaatttca 4560 actacttttt cagctttagg gtttttagat acgtttgtac cacaattgag catgggaggg 4620 agaggggtga gcctaagcag tgatggctga tttctgtcac gtctgtcatg tgtcccccag 4680 tacctccaga ggtaactgtg ctcacgaaca gccctgtgga actgagagag cccaacgtcc 4740 tcatctgttt catcgacaag ttcaccccac cagtggtcaa tgtcacgtgg cttcgaaatg 4800 gaaaacctgt caccacagga gtgtcagaga cagtcttcct gcccagggaa gaccaccttt 4860 tccgcaagtt ccactatctc cccttcctgc cctcaactga ggacgtttac gactgcaggg 4920 tggagcactg gggcttggat gagcctcttc tcaagcactg gggtatggac caacactcaa 4980 tctcctttat ttcaaggttt cctcctatga tgcttgtgtg aaactcggtg ttctaactgt 5040 ttcataatat ctgctacaat taatataact gtcttctcct actatccagc ttcctccttt 5100 ttttaatctg taattctctc aatacatcat tctgtcttcc tcttctttaa tctatgaata 5160 acttttctct ttattaagaa ccctacattt gattctgagt gttacttctt cccacactca 5220 ttaccatgta ctctgcctta tctcccccca gagtttgatg ctccaagccc tctcccagag 5280 actacagaga acgtggtgtg tgccctgggc ctgactgtgg gtctggtggg catcattatt 5340 gggaccatct tcatcatcaa gggagtgcgc aaaagcaatg cagcagaacg cagggggcct 5400 ctgtaaggca catggaggtg agttaggtgt ggtcagagga agacatatat ggagatatct 5460 gagggaggaa aacagggtgg ggaaaggaaa tgtaatgcat ttaagagaca aggtaggaac 5520 agatgtggct cttgatttct ctttgctaga atgaatcaga cattggtatc atctggtatc 5580 ccaaagcttc agggtctgtc atccctttct atagacgggc accttgatca cggctccagt 5640 cttagaaatc atctccagta cctaaaacca ttgtttcaca ttagaatact gagtctaggg 5700 atctagaaaa tacattagaa tatggagtct agggatctag aaaatactga gtctagggat 5760 ctagaaaaat aagcctcaag atttgggcac atcctagctt gtatttcctg gggcaggtca 5820 tcagttcaga agcatttcca gatcctggct cctttcaggt tagggtcaat tcattgcatg 5880 aaatgggaat ctcttagagg ccaatgcctg cttttgcttc tttagtctca aatgtagtat 5940 gagaaactct aaaaaaaggt aaagcatggt tgcttattat gttcagttgg agagtaggaa 6000 ctaactgtat acagttagtt catgttggaa aggttagatg aacattgaaa gaattttgca 6060 aagtcaaagg attaagagag aagaggaagg aatctgaagc aaggagctca aaacggatct 6120 taaattcctt ggtaactatg tgtgtcttgc tataggtgat ggtgtttctt agagagaaga 6180 tcactgaaga aacttctgct ttaatgactt tacaaagctg gcaatattac aatccttgac 6240 ctcagtgaaa gcagtcatct tcagcgtttt ccagccctat agccacccca agtgtggtta 6300 tgcctcctcg attgctccgt actctaacat ctagctggct tccctgtcta ttgccttttc 6360 ctgtatctat tttcctctat ttcctatcat tttattatca ccatgcaatg cctctggaat 6420 aaaacataca ggagtctgtc tctgctatgg aatgccccat ggggcatctc ttgtgtactt 6480 attgtttaag gtttcctcaa actgtgattt ttctgaacac aataaactat tttgatgatc 6540 ttgggtggaa tttttggtgt ttaagccagt tctttgggtg gcggtggggg gtggggagtc 6600 ggtcctgggg aatatatgtg atcctttccc ggtaaaatat ctgaatgttg aatttatctt 6660 ataaattcta gaattcatca gacatatccc ggttcatttg ggcttggtct cattttgtgc 6720 atctgcaggc aaccctcttg ttgtggtcta gtcctcatca ggaaaaccta aagtggggtt 6780 ggtttgttgg gagatctcta ctgagcaatg atataactct gtcttcagta gagtgaatct 6840 gaaaccccaa ggtatggatc tcagaatgca tgggatagag gggagcagat ggggttagag 6900 tggggagaag gaagacagaa gaatccataa acattgcagg atttacatat caacatcgtt 6960 cattccagat ttaatgagca aagaggttgg acactgaaga ctggccttac ccattctgtt 7020 agacatagtc tcagatgcct attttattac cgagagagta gtctgactga ttcttgaaac 7080 caccttatat ttgaagatgt gtctttgagt ggaaaagctg agtgaaattt ggggttgggg 7140 agaaagatat gacattaaga tgagaggaag gaatatttga aacacaatga actgttgctc 7200 atttgtctat aaaactatga cttgatattt atctctaaaa tagtttctag aacctgccat 7260 aaaccactaa gataaactat tcatgatagt gtggtagact gcaaataaat gctgttgaaa 7320 tgagttaggc ttgggtttca tcttggctgt atcatttact agctatgttt tcactggtat 7380 cttacttaac ttagcctcac attactcatg aaaatactgg tgttaatttt tactacattg 7440 aattaatatc agaattaaaa ggaaaacgca agcaaagtaa ttagatacat gcttagtgat 7500 aataaaatat tgcaaaaaat tatacattct gttgtttttc tcaaaatttc tatagactga 7560 tgataaaaat ctaagagaag ctaaacaaaa caaggataaa ccaaagcatc atgacattct 7620 aagccttact aataaataag aagtttctcg gctgggcacg gtggctcacg cctgtaatcc 7680 agcactttgg gaggccgagg tgggcggatc acaaggtcag gaaatcaaga ccatcctggc 7740 caacatggtg aaaccccatc tctactaaaa atacaaaaat tagccaggcg tggtgatagg 7800 cgcctgtaat cccagctact ctggaggttg aggcaggaga atctcttgaa tccgggaggc 7860 agaggttgca gtgagccgag atcgcaccac tgcgctcctg cctggcaaca gactgagact 7920 ccgtctcaaa aaaaaaaaaa aaaaaaagtt tctctactgt tggttcagag aatcaaagca 7980 gaatcttgag actactgatg gtagaatagg tacgagtgtc tttcttacat gactacaaac 8040 tttattataa aataaatagc ttaacacaga gaatacacta aaacttagac aagcatggat 8100 taagaaagca aaaagtaaac ccatatacta ccatgtaaga aaaccatttt tggccaggtg 8160 cggtggctca cgcctgtaat cccagcactt tgggaggccg aggcgggcgg atcacgaggt 8220 caggagatcg agaccatcct ggctaacatg gtgaaacccc gtctctacta aaaaaaaaca 8280 aaacaaaaaa ttagccgggt gtggtggcgg gtgcctgtag tcccagctac tcgagaagtt 8340 gaggcaggaa aatggcgtga acccaagagg cagagcttgc agtaagccga gatcacacca 8400 ctgcactcca gcctgggcga cagagcgaga ctccatctca aaaaaaagaa aaaaaaaaaa 8460 aaaaaaaaaa aaaggaaaac cattttaata gacttttatt tttagagctg ttttaagcta 8520 acagaaaaat tgcagaaatt gtatacagag ctcccccacc cccagtttct acaatgctta 8580 acatcctgta ttaatgtggt acacttgtta caattgatga accaatacta ataattatta 8640 ttaactaaaa ttcatagtta tacgagggtt cactctgtat ta 8682 // ID OW496041; SV 1; linear; genomic DNA; STD; HUM; 8682 BP. XX AC OW496041; XX PR Project:PRJEB52229; XX DT 28-APR-2022 (Rel. 144, Created) DT 29-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DRA gene for MHC class II antigen, allele DE HLA-DRA*01:01:01:NEW1 XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Turner R T.; RT ; RL Submitted (08-APR-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, The Royal Free Hospital, Pond Street, RL London, NW3 2QU, United Kingdom XX DR MD5; fd5015834bdbc63251d52c4b35eb0827. XX FH Key Location/Qualifiers FH FT source 1..8682 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="JAP_NF" FT /db_xref="taxon:9606" FT CDS join(1449..1530,3944..4189,4681..4962,5252..5406) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH2618645.1" FT /translation="MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSG FT EFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNY FT TPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFL FT PREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL FT GLTVGLVGIIIGTIFIIKGVRKSNAAERRGPL" FT exon 1449..1530 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT intron 1531..3943 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT exon 3944..4189 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT intron 4190..4680 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT exon 4681..4962 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT intron 4963..5251 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT exon 5252..5406 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=4 XX SQ Sequence 8682 BP; 2534 A; 1810 C; 1847 G; 2491 T; 0 other; ctccctcact gccaggtcac tcttcatgga agtatttgta ttccagtcct ttctgtggaa 60 agaaattaac attctccttt tcataacact gtatcttcag aaacaagaga gtcgaagtct 120 cctaattttc aggactgtct atgttgaaca tcaaaatata ttctttagag cagatcttta 180 ataatcatat gacaagagaa aaactttcat aatcttatga catgagggaa ggaatattaa 240 agccgttctg tgggttatta tctctaacgt tcccaataga ataggctttg ccagctgggt 300 gcggtggctc atgcctgtaa tcccagcact ttgcgaggcc aaggcgggca aatcacgagg 360 tcaggagtct gagaccagcc tgaccaacat ggtgaaaccc cgtctctact aaaaatacaa 420 aaattagccg ggcatggtgg tgggcgcctg taatcccagc tactcaggag gctgaggcag 480 gagaatcgct tgaacccggg aggcggagat tacaatgagc tgagatcaca ccaccaactc 540 cagcttgggc gacagagcaa gactctgtct aaaaaaaaaa aaaaaaaaaa agaataggct 600 ttgcccacta tactctctca tattcattga cctgaatcct caaatgaggt gtgtccatta 660 gtcaactcca atctcttgtc atatataaga tggtagagat gagaagaagg tagctccttt 720 acagcccact atttccacta actactacct gtgtttcaag atacagcctt tcatccttct 780 ccagtgttga gagtgttgaa cctcagagtt tctcctctca ttttctctaa atgagataca 840 atgccagcca tcccaagctc ttggcctgag ttgatcatct tgaagtctag gactccaaga 900 agcatgaaag agcttcttta gtgaagctat gtcctcagta ctgccaaaat tcagacaatc 960 tccatggcct gacaatttac cttctatttg ggtaatttat tgtcccttac gcaaactctc 1020 caactgtcat tgcacagaca tatgatctgt atttagctct cactttaggt gtttccattg 1080 attctattct cactaatgtg cttcaggtat atccctgtct agaagtcaga ttggggttaa 1140 agagtctgtc cgtgattgac taacagtctt aaatacttga tttgttgttg ttgttgtcct 1200 gtttgtttaa gaactttact tctttatcca atgaacggag tatcttgtgt cctggaccct 1260 ttgcaagaac ccttccccta gcaacagatg cgtcatctca aaatattttt ctgattggcc 1320 aaagagtaat tgatttgcat tttaatggtc agactctatt acaccccaca ttctcttttc 1380 ttttattctt gtctgttctg cctcactccc gagctctact gactcccaaa agagcgccca 1440 agaagaaaat ggccataagt ggagtccctg tgctaggatt tttcatcata gctgtgctga 1500 tgagcgctca ggaatcatgg gctatcaaag gtaggtgctg agggaatgaa atctgggacg 1560 atagactacg aagcattgga gaaaagacct atggacattt ggaagataat gtgtggagtg 1620 aaagaatagt gtgacaggta ttatgtggtc tcgacagaaa gtataacaaa ttgtggtttg 1680 gtggagttct tccctcacca caaactgaag taagtcaaat ttggtttaga gggtcaaaac 1740 tgagttgtgt attgatgaat agcacggtcc tgctacaagc caaactgggg gtgggggtgg 1800 gggtggggga ggaagaatat tttctggcaa gcattaacaa gttatatttc tgggctttaa 1860 ttattctttc tggaaaatta gtaaaattaa aaactaaaaa ccacacatag ttttgctaga 1920 attaaatgaa aaaaaaagtt attagccctg ttcttatctg aatacatgat acagtagtta 1980 ttttttggag tgtaaatcct gtcggtatat attgagcaca tatattgtgt tgaagattac 2040 tagaaggaaa agtcatcaaa aagcaacaat ttaccccagg aaaaggggag ggaaggcatg 2100 ctgatatgag ttgcctcatg ggacagtgat agccattccc tgccttccca tctccatggt 2160 acagcagatc ttatatcatg ttaacttagt aatatttcca agagagtaga aaaataagga 2220 aggaaatggg gaatctgata ttattctctc tcatctccag agcaacattg gtgctgttgt 2280 aaagatgtac tgtagaaaag tattcttcac ccagcgtgac ccccacagaa ggtgtcaggt 2340 agacttgaaa taagcaaagt aataacccag ctcccatacc catagtggca attgtagatt 2400 tctattgccc caaaagagcc atacataggg atacttacct agaaagacag aggctcttcc 2460 cttggtttgt gaagaggcag ctagtatatt tgtgtgtgtt tgcatagatg caaacggtaa 2520 ataaattcct aggtttatca atacacagtc aaacattaaa atctctcatc ttggctgggc 2580 acggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 2640 tcaagagatc gagaccgtcc tgggcaacat ggtgaaaccc cgtctctact aaaaatacaa 2700 aaaattagct gggtatggtg gcacacgcct gtagtcccag ctactcggga ggctgaggca 2760 ggaggattgc ttgagcccgg gaggcggagg ttgcagtgag ctgagatggt gccactgcac 2820 tccagcctgg cgatagagca agactccgtc tcaaacaacc aaaccaaaac aaaacaaaat 2880 atctcacctt atctttgaag actaaggaaa aaaaaaatct cccactcatc gatacactcc 2940 acagaggcag catactctcc cagtgtagct ttctcttttc atgttcatta ttcccttggt 3000 gttggttatt ctcaatgtca atcgtaacag aacatcttcc ataataacag tcccaattta 3060 aggagcatta agataaaagg tggaattgcc aaggtcaatc cagacgagaa ccttctcata 3120 gaggtaacca ccgtgtgggt ttggatgctg ggaagcaggg ggactatgac gctacaaggt 3180 ctcagtctta atttttggag tacttcagtc cccaggtata ttttccatag atttggccct 3240 taaataaaaa gaagcttctg actctaaaat gtaaacagtg cttgttacag tcttgttgat 3300 atattaagaa attactcacc ttatctcatt taatcttaaa aacaaacccc tgacaggatc 3360 aaaaccacag cagggctaca taataggaaa actatacata aataggtaga ataatctgct 3420 caggatcact aggtaagttg ctgaataaga attcaagatg tttttgatcc cagagtttaa 3480 aacccaacct ttcaaacagt gtttccttct tcttagagta caatgttctg agaaagagat 3540 cctctggaat tctggcctaa gtgtatttaa tgcccgggta aagaaagtga gagaacattt 3600 ctctttaggg gctgctgctg gatttctaaa aagaaaataa tttctcagct agtaacatgg 3660 agccaaacaa cagcttcaca agactctggg ttctttagcc ctcatctcct tcaatccacc 3720 ctctttataa ccagtccttc ttgtttttcc cctcccagct ttgttcagca gcatgccctt 3780 cacccagacc ttgtcttgtc actcatccct actcgccatc attctttcat tcctcttggc 3840 ccaatctctc tccaccactt cctgcctaca tgtatgtagg ttattcattt ccctctcttg 3900 attcccccca cccaactctc tttctccatt tcttgccttt cagaagaaca tgtgatcatc 3960 caggccgagt tctatctgaa tcctgaccaa tcaggcgagt ttatgtttga ctttgatggt 4020 gatgagattt tccatgtgga tatggcaaag aaggagacgg tctggcggct tgaagaattt 4080 ggacgatttg ccagctttga ggctcaaggt gcattggcca acatagctgt ggacaaagcc 4140 aacctggaaa tcatgacaaa gcgctccaac tatactccga tcaccaatgg tacctccctc 4200 tctgctgcac tcctggacat gggaatccat agtttgaaag tagttgcttc agctctttgt 4260 gttagattat tgtaactgat tttccctcca agggcctaac cttgccatta acaagcccca 4320 aattctcatg ccagaggtct gagaacttta tgggtttgat cctatcttgt tgtgctcaag 4380 tcttgtctct gtcatccatg gtctcctacg aagtcattgc cctaagttca tgctagggga 4440 gccagaaggg aagtccttgg atatcttata cctcaatatt ggctcaattt cttggggagg 4500 gggtgctgtc agagattgtt atctgaggat gtgacataga tttctcaggg cacaatttca 4560 actacttttt cagctttagg gtttttagat acgtttgtac cacaattgag catgggaggg 4620 agaggggtga gcctaagcag tgatggctga tttctgtcac gtctgtcatg tgtcccccag 4680 tacctccaga ggtaactgtg ctcacgaaca gccctgtgga actgagagag cccaacgtcc 4740 tcatctgttt catcgacaag ttcaccccac cagtggtcaa tgtcacgtgg cttcgaaatg 4800 gaaaacctgt caccacagga gtgtcagaga cagtcttcct gcccagggaa gaccaccttt 4860 tccgcaagtt ccactatctc cccttcctgc cctcaactga ggacgtttac gactgcaggg 4920 tggagcactg gggcttggat gagcctcttc tcaagcactg gggtatggac caacactcaa 4980 tctcctttat ttcaaggttt cctcctatga tgcttgtgtg aaactcggtg ttctaactgt 5040 ttcataatat ctgctacaat taatataact gtcttctcct actatccagc ttcctccttt 5100 ttttaatctg taattctctc aatacatcat tctgtcttcc tcttctttaa tctatgaata 5160 acttttctct ttattaagaa ccctacattt gattctgagt gttacttctt cccacactca 5220 ttaccatgta ctctgcctta tctcccccca gagtttgatg ctccaagccc tctcccagag 5280 actacagaga acgtggtgtg tgccctgggc ctgactgtgg gtctggtggg catcattatt 5340 gggaccatct tcatcatcaa gggagtgcgc aaaagcaatg cagcagaacg cagggggcct 5400 ctgtaaggca catggaggtg agttaggtgt ggtcagagga agacatatat ggagatatct 5460 gagggaggaa aacagggtgg ggaaaggaaa tgtaatgcat ttaagagaca aggtaggaac 5520 agatgtggct cttgatttct ctttgctaga atgaatcaga cattggtatc atctggtatc 5580 ccaaagcttc agggtctgtc atccctttct atagacgggc accttgatca cggctccagt 5640 cttagaaatc atctccagta cctaaaacca ttgtttcaca ttagaatact gagtctaggg 5700 atctagaaaa tacattagaa tatggagtct agggatctag aaaatactga gtctagggat 5760 ctagaaaaat aagcctcaag atttgggcac atcctagctt gtatttcctg gggcaggtca 5820 tcagttcaga agcatttcca gatcctggct cctttcaggt tagggtcaat tcattgcatg 5880 aaatgggaat ctcttagagg ccaatgcctg cttttgcttc tttagtctca aatgtagtat 5940 gagaaactct aaaaaaaggt aaagcatggt tgcttattat gttcagttgg agagtaggaa 6000 ctaactgtat acagttagtt catgttggaa aggttagatg aacattgaaa gaattttgca 6060 aagtcaaagg attaagagag aagaggaagg aatctgaagc aaggagctca aaacggatct 6120 taaattcctt ggtaactatg tgtgtcttgc tataggtgat ggtgtttctt agagagaaga 6180 tcactgaaga aacttctgct ttaatgactt tacaaagctg gcaatattac aatccttgac 6240 ctcagtgaaa gcagtcatct tcagcgtttt ccagccctat agccacccca agtgtggtta 6300 tgcctcctcg attgctccgt actctaacat ctagctggct tccctgtcta ttgccttttc 6360 ctgtatctat tttcctctat ttcctatcat tttattatca ccatgcaatg cctctggaat 6420 aaaacataca ggagtctgtc tctgctatgg aatgccccat ggggcatctc ttgtgtactt 6480 attgtttaag gtttcctcaa actgtgattt ttctgaacac aataaactat tttgatgatc 6540 ttgggtggaa tttttggtgt ttaagccagt tctttgggtg gcggtggggg gtggggagtc 6600 ggtcctgggg aatatatgtg atcctttccc ggtaaaatat ctgaatgttg aatttatctt 6660 ataaattcta gaattcatca gacatatccc ggttcatttg ggcttggtct cattttgtgc 6720 atctgcaggc aaccctcttg ttgtggtcta gtcctcatca ggaaaaccta aagtggggtt 6780 ggtttgttgg gagatctcta ctgagcaatg atataactct gtcttcagta gagtgaatct 6840 gaaaccccaa ggtatggatc tcagaatgca tgggatagag gggagcagat ggggttagag 6900 tggggagaag gaagacagaa gaatccataa acattgcagg atttacatat caacatcgtt 6960 cattccagat ttaatgagca aagaggttgg acactgaaga ctggccttac ccattctgtt 7020 agacatagtc tcagatgcct attttattac cgagagagta gtctgactga ttcttgaaac 7080 caccttatat ttgaagatgt gtctttgagt ggaaaagctg agtgaaattt ggggttgggg 7140 agaaagatat gacattaaga tgagaggaag gaatatttga aacacaatga actgttgctc 7200 atttgtctat aaaactatga cttgatattt atctctaaaa tagtttctag aacctgccat 7260 aaaccactaa gataaactat tcatgatagt gtggtagact gcaaataaat gctgttgaaa 7320 tgagttaggc ttgggtttca tcttggctgt atcatttact agctatgttt tcactggtat 7380 cttacttaac ttagcctcac attactcatg aaaatactgg tgttaatttt tactacattg 7440 aattaatatc agaattaaaa ggaaaacgca agcaaagtaa ttagatacat gcttagtgat 7500 aataaaatat tgcaaaaaat tatacattct gttgtttttc tcaaaatttc tatagactga 7560 tgataaaaat ctaagagaag ctaaacaaaa caaggataaa ccaaagcatc atgacattct 7620 aagccttact aataaataag aagtttctcg gctgggcacg gtggctcacg cctgtaatcc 7680 agcactttgg gaggccgagg tgggcggatc acaaggtcag gaaatcaaga ccatcctggc 7740 caacatggtg aaaccccatc tctactaaaa atacaaaaat tagccaggcg tggtgatagg 7800 cgcctgtaat cccagctact ctggaggttg aggcaggaga atctcttgaa tccgggaggc 7860 agaggttgca gtgagccgag atcgcaccac tgcgctcctg cctggcaaca gactgagact 7920 ccgtctcaaa aaaaaaaaaa aaaaaaagtt tctctactgt tggttcagag aatcaaagca 7980 gaatcttgag actactgatg gtagaatagg tacgagtgtc tttcttacat gactacaaac 8040 tttattataa aataaatagc ttaacacaga gaatacacta aaacttagac aagcatggat 8100 taagaaagca aaaagtaaac ccatatacta ccatgtaaga aaaccatttt tggccaggtg 8160 cggtggctca cgcctgtaat cccagcactt tgggaggccg aggcgggcgg atcacgaggt 8220 caggagatcg agaccatcct ggctaacatg gtgaaacccc gtctctacta aaaaaaaaca 8280 aaacaaaaaa ttagccgggt gtggtggcgg gtgcctgtag tcccagctac tcgagaagtt 8340 gaggcaggaa aatggcgtga acccaagagg cagagcttgc agtaagccga gatcacacca 8400 ctgcactcca gcctgggcga cagagcgaga ctccatctca aaaaaaagaa aaaaaaaaaa 8460 aaaaaaaaaa aaaggaaaac cattttaata gacttttatt tttagagctg ttttaagcta 8520 acagaaaaat tgcagaaatt gtatacagag ctcccccacc cccagtttct acaatgctta 8580 acatcctgta ttaatgtggt acacttgtta caattgatga accaatacta ataattatta 8640 ttaactaaaa ttcatagtta tacgagggtt cactctgtat ta 8682 // ID OW496046; SV 1; linear; genomic DNA; STD; HUM; 8682 BP. XX AC OW496046; XX PR Project:PRJEB52229; XX DT 28-APR-2022 (Rel. 144, Created) DT 29-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DRA gene for MHC class II antigen, allele DE HLA-DRA*01:01:01:NEW1 XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Turner R T.; RT ; RL Submitted (08-APR-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, The Royal Free Hospital, Pond Street, RL London, NW3 2QU, United Kingdom XX DR MD5; fd5015834bdbc63251d52c4b35eb0827. XX FH Key Location/Qualifiers FH FT source 1..8682 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="LWAGS" FT /db_xref="taxon:9606" FT CDS join(1449..1530,3944..4189,4681..4962,5252..5406) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH2618650.1" FT /translation="MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSG FT EFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNY FT TPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFL FT PREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL FT GLTVGLVGIIIGTIFIIKGVRKSNAAERRGPL" FT exon 1449..1530 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT intron 1531..3943 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT exon 3944..4189 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT intron 4190..4680 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT exon 4681..4962 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT intron 4963..5251 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT exon 5252..5406 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=4 XX SQ Sequence 8682 BP; 2534 A; 1810 C; 1847 G; 2491 T; 0 other; ctccctcact gccaggtcac tcttcatgga agtatttgta ttccagtcct ttctgtggaa 60 agaaattaac attctccttt tcataacact gtatcttcag aaacaagaga gtcgaagtct 120 cctaattttc aggactgtct atgttgaaca tcaaaatata ttctttagag cagatcttta 180 ataatcatat gacaagagaa aaactttcat aatcttatga catgagggaa ggaatattaa 240 agccgttctg tgggttatta tctctaacgt tcccaataga ataggctttg ccagctgggt 300 gcggtggctc atgcctgtaa tcccagcact ttgcgaggcc aaggcgggca aatcacgagg 360 tcaggagtct gagaccagcc tgaccaacat ggtgaaaccc cgtctctact aaaaatacaa 420 aaattagccg ggcatggtgg tgggcgcctg taatcccagc tactcaggag gctgaggcag 480 gagaatcgct tgaacccggg aggcggagat tacaatgagc tgagatcaca ccaccaactc 540 cagcttgggc gacagagcaa gactctgtct aaaaaaaaaa aaaaaaaaaa agaataggct 600 ttgcccacta tactctctca tattcattga cctgaatcct caaatgaggt gtgtccatta 660 gtcaactcca atctcttgtc atatataaga tggtagagat gagaagaagg tagctccttt 720 acagcccact atttccacta actactacct gtgtttcaag atacagcctt tcatccttct 780 ccagtgttga gagtgttgaa cctcagagtt tctcctctca ttttctctaa atgagataca 840 atgccagcca tcccaagctc ttggcctgag ttgatcatct tgaagtctag gactccaaga 900 agcatgaaag agcttcttta gtgaagctat gtcctcagta ctgccaaaat tcagacaatc 960 tccatggcct gacaatttac cttctatttg ggtaatttat tgtcccttac gcaaactctc 1020 caactgtcat tgcacagaca tatgatctgt atttagctct cactttaggt gtttccattg 1080 attctattct cactaatgtg cttcaggtat atccctgtct agaagtcaga ttggggttaa 1140 agagtctgtc cgtgattgac taacagtctt aaatacttga tttgttgttg ttgttgtcct 1200 gtttgtttaa gaactttact tctttatcca atgaacggag tatcttgtgt cctggaccct 1260 ttgcaagaac ccttccccta gcaacagatg cgtcatctca aaatattttt ctgattggcc 1320 aaagagtaat tgatttgcat tttaatggtc agactctatt acaccccaca ttctcttttc 1380 ttttattctt gtctgttctg cctcactccc gagctctact gactcccaaa agagcgccca 1440 agaagaaaat ggccataagt ggagtccctg tgctaggatt tttcatcata gctgtgctga 1500 tgagcgctca ggaatcatgg gctatcaaag gtaggtgctg agggaatgaa atctgggacg 1560 atagactacg aagcattgga gaaaagacct atggacattt ggaagataat gtgtggagtg 1620 aaagaatagt gtgacaggta ttatgtggtc tcgacagaaa gtataacaaa ttgtggtttg 1680 gtggagttct tccctcacca caaactgaag taagtcaaat ttggtttaga gggtcaaaac 1740 tgagttgtgt attgatgaat agcacggtcc tgctacaagc caaactgggg gtgggggtgg 1800 gggtggggga ggaagaatat tttctggcaa gcattaacaa gttatatttc tgggctttaa 1860 ttattctttc tggaaaatta gtaaaattaa aaactaaaaa ccacacatag ttttgctaga 1920 attaaatgaa aaaaaaagtt attagccctg ttcttatctg aatacatgat acagtagtta 1980 ttttttggag tgtaaatcct gtcggtatat attgagcaca tatattgtgt tgaagattac 2040 tagaaggaaa agtcatcaaa aagcaacaat ttaccccagg aaaaggggag ggaaggcatg 2100 ctgatatgag ttgcctcatg ggacagtgat agccattccc tgccttccca tctccatggt 2160 acagcagatc ttatatcatg ttaacttagt aatatttcca agagagtaga aaaataagga 2220 aggaaatggg gaatctgata ttattctctc tcatctccag agcaacattg gtgctgttgt 2280 aaagatgtac tgtagaaaag tattcttcac ccagcgtgac ccccacagaa ggtgtcaggt 2340 agacttgaaa taagcaaagt aataacccag ctcccatacc catagtggca attgtagatt 2400 tctattgccc caaaagagcc atacataggg atacttacct agaaagacag aggctcttcc 2460 cttggtttgt gaagaggcag ctagtatatt tgtgtgtgtt tgcatagatg caaacggtaa 2520 ataaattcct aggtttatca atacacagtc aaacattaaa atctctcatc ttggctgggc 2580 acggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 2640 tcaagagatc gagaccgtcc tgggcaacat ggtgaaaccc cgtctctact aaaaatacaa 2700 aaaattagct gggtatggtg gcacacgcct gtagtcccag ctactcggga ggctgaggca 2760 ggaggattgc ttgagcccgg gaggcggagg ttgcagtgag ctgagatggt gccactgcac 2820 tccagcctgg cgatagagca agactccgtc tcaaacaacc aaaccaaaac aaaacaaaat 2880 atctcacctt atctttgaag actaaggaaa aaaaaaatct cccactcatc gatacactcc 2940 acagaggcag catactctcc cagtgtagct ttctcttttc atgttcatta ttcccttggt 3000 gttggttatt ctcaatgtca atcgtaacag aacatcttcc ataataacag tcccaattta 3060 aggagcatta agataaaagg tggaattgcc aaggtcaatc cagacgagaa ccttctcata 3120 gaggtaacca ccgtgtgggt ttggatgctg ggaagcaggg ggactatgac gctacaaggt 3180 ctcagtctta atttttggag tacttcagtc cccaggtata ttttccatag atttggccct 3240 taaataaaaa gaagcttctg actctaaaat gtaaacagtg cttgttacag tcttgttgat 3300 atattaagaa attactcacc ttatctcatt taatcttaaa aacaaacccc tgacaggatc 3360 aaaaccacag cagggctaca taataggaaa actatacata aataggtaga ataatctgct 3420 caggatcact aggtaagttg ctgaataaga attcaagatg tttttgatcc cagagtttaa 3480 aacccaacct ttcaaacagt gtttccttct tcttagagta caatgttctg agaaagagat 3540 cctctggaat tctggcctaa gtgtatttaa tgcccgggta aagaaagtga gagaacattt 3600 ctctttaggg gctgctgctg gatttctaaa aagaaaataa tttctcagct agtaacatgg 3660 agccaaacaa cagcttcaca agactctggg ttctttagcc ctcatctcct tcaatccacc 3720 ctctttataa ccagtccttc ttgtttttcc cctcccagct ttgttcagca gcatgccctt 3780 cacccagacc ttgtcttgtc actcatccct actcgccatc attctttcat tcctcttggc 3840 ccaatctctc tccaccactt cctgcctaca tgtatgtagg ttattcattt ccctctcttg 3900 attcccccca cccaactctc tttctccatt tcttgccttt cagaagaaca tgtgatcatc 3960 caggccgagt tctatctgaa tcctgaccaa tcaggcgagt ttatgtttga ctttgatggt 4020 gatgagattt tccatgtgga tatggcaaag aaggagacgg tctggcggct tgaagaattt 4080 ggacgatttg ccagctttga ggctcaaggt gcattggcca acatagctgt ggacaaagcc 4140 aacctggaaa tcatgacaaa gcgctccaac tatactccga tcaccaatgg tacctccctc 4200 tctgctgcac tcctggacat gggaatccat agtttgaaag tagttgcttc agctctttgt 4260 gttagattat tgtaactgat tttccctcca agggcctaac cttgccatta acaagcccca 4320 aattctcatg ccagaggtct gagaacttta tgggtttgat cctatcttgt tgtgctcaag 4380 tcttgtctct gtcatccatg gtctcctacg aagtcattgc cctaagttca tgctagggga 4440 gccagaaggg aagtccttgg atatcttata cctcaatatt ggctcaattt cttggggagg 4500 gggtgctgtc agagattgtt atctgaggat gtgacataga tttctcaggg cacaatttca 4560 actacttttt cagctttagg gtttttagat acgtttgtac cacaattgag catgggaggg 4620 agaggggtga gcctaagcag tgatggctga tttctgtcac gtctgtcatg tgtcccccag 4680 tacctccaga ggtaactgtg ctcacgaaca gccctgtgga actgagagag cccaacgtcc 4740 tcatctgttt catcgacaag ttcaccccac cagtggtcaa tgtcacgtgg cttcgaaatg 4800 gaaaacctgt caccacagga gtgtcagaga cagtcttcct gcccagggaa gaccaccttt 4860 tccgcaagtt ccactatctc cccttcctgc cctcaactga ggacgtttac gactgcaggg 4920 tggagcactg gggcttggat gagcctcttc tcaagcactg gggtatggac caacactcaa 4980 tctcctttat ttcaaggttt cctcctatga tgcttgtgtg aaactcggtg ttctaactgt 5040 ttcataatat ctgctacaat taatataact gtcttctcct actatccagc ttcctccttt 5100 ttttaatctg taattctctc aatacatcat tctgtcttcc tcttctttaa tctatgaata 5160 acttttctct ttattaagaa ccctacattt gattctgagt gttacttctt cccacactca 5220 ttaccatgta ctctgcctta tctcccccca gagtttgatg ctccaagccc tctcccagag 5280 actacagaga acgtggtgtg tgccctgggc ctgactgtgg gtctggtggg catcattatt 5340 gggaccatct tcatcatcaa gggagtgcgc aaaagcaatg cagcagaacg cagggggcct 5400 ctgtaaggca catggaggtg agttaggtgt ggtcagagga agacatatat ggagatatct 5460 gagggaggaa aacagggtgg ggaaaggaaa tgtaatgcat ttaagagaca aggtaggaac 5520 agatgtggct cttgatttct ctttgctaga atgaatcaga cattggtatc atctggtatc 5580 ccaaagcttc agggtctgtc atccctttct atagacgggc accttgatca cggctccagt 5640 cttagaaatc atctccagta cctaaaacca ttgtttcaca ttagaatact gagtctaggg 5700 atctagaaaa tacattagaa tatggagtct agggatctag aaaatactga gtctagggat 5760 ctagaaaaat aagcctcaag atttgggcac atcctagctt gtatttcctg gggcaggtca 5820 tcagttcaga agcatttcca gatcctggct cctttcaggt tagggtcaat tcattgcatg 5880 aaatgggaat ctcttagagg ccaatgcctg cttttgcttc tttagtctca aatgtagtat 5940 gagaaactct aaaaaaaggt aaagcatggt tgcttattat gttcagttgg agagtaggaa 6000 ctaactgtat acagttagtt catgttggaa aggttagatg aacattgaaa gaattttgca 6060 aagtcaaagg attaagagag aagaggaagg aatctgaagc aaggagctca aaacggatct 6120 taaattcctt ggtaactatg tgtgtcttgc tataggtgat ggtgtttctt agagagaaga 6180 tcactgaaga aacttctgct ttaatgactt tacaaagctg gcaatattac aatccttgac 6240 ctcagtgaaa gcagtcatct tcagcgtttt ccagccctat agccacccca agtgtggtta 6300 tgcctcctcg attgctccgt actctaacat ctagctggct tccctgtcta ttgccttttc 6360 ctgtatctat tttcctctat ttcctatcat tttattatca ccatgcaatg cctctggaat 6420 aaaacataca ggagtctgtc tctgctatgg aatgccccat ggggcatctc ttgtgtactt 6480 attgtttaag gtttcctcaa actgtgattt ttctgaacac aataaactat tttgatgatc 6540 ttgggtggaa tttttggtgt ttaagccagt tctttgggtg gcggtggggg gtggggagtc 6600 ggtcctgggg aatatatgtg atcctttccc ggtaaaatat ctgaatgttg aatttatctt 6660 ataaattcta gaattcatca gacatatccc ggttcatttg ggcttggtct cattttgtgc 6720 atctgcaggc aaccctcttg ttgtggtcta gtcctcatca ggaaaaccta aagtggggtt 6780 ggtttgttgg gagatctcta ctgagcaatg atataactct gtcttcagta gagtgaatct 6840 gaaaccccaa ggtatggatc tcagaatgca tgggatagag gggagcagat ggggttagag 6900 tggggagaag gaagacagaa gaatccataa acattgcagg atttacatat caacatcgtt 6960 cattccagat ttaatgagca aagaggttgg acactgaaga ctggccttac ccattctgtt 7020 agacatagtc tcagatgcct attttattac cgagagagta gtctgactga ttcttgaaac 7080 caccttatat ttgaagatgt gtctttgagt ggaaaagctg agtgaaattt ggggttgggg 7140 agaaagatat gacattaaga tgagaggaag gaatatttga aacacaatga actgttgctc 7200 atttgtctat aaaactatga cttgatattt atctctaaaa tagtttctag aacctgccat 7260 aaaccactaa gataaactat tcatgatagt gtggtagact gcaaataaat gctgttgaaa 7320 tgagttaggc ttgggtttca tcttggctgt atcatttact agctatgttt tcactggtat 7380 cttacttaac ttagcctcac attactcatg aaaatactgg tgttaatttt tactacattg 7440 aattaatatc agaattaaaa ggaaaacgca agcaaagtaa ttagatacat gcttagtgat 7500 aataaaatat tgcaaaaaat tatacattct gttgtttttc tcaaaatttc tatagactga 7560 tgataaaaat ctaagagaag ctaaacaaaa caaggataaa ccaaagcatc atgacattct 7620 aagccttact aataaataag aagtttctcg gctgggcacg gtggctcacg cctgtaatcc 7680 agcactttgg gaggccgagg tgggcggatc acaaggtcag gaaatcaaga ccatcctggc 7740 caacatggtg aaaccccatc tctactaaaa atacaaaaat tagccaggcg tggtgatagg 7800 cgcctgtaat cccagctact ctggaggttg aggcaggaga atctcttgaa tccgggaggc 7860 agaggttgca gtgagccgag atcgcaccac tgcgctcctg cctggcaaca gactgagact 7920 ccgtctcaaa aaaaaaaaaa aaaaaaagtt tctctactgt tggttcagag aatcaaagca 7980 gaatcttgag actactgatg gtagaatagg tacgagtgtc tttcttacat gactacaaac 8040 tttattataa aataaatagc ttaacacaga gaatacacta aaacttagac aagcatggat 8100 taagaaagca aaaagtaaac ccatatacta ccatgtaaga aaaccatttt tggccaggtg 8160 cggtggctca cgcctgtaat cccagcactt tgggaggccg aggcgggcgg atcacgaggt 8220 caggagatcg agaccatcct ggctaacatg gtgaaacccc gtctctacta aaaaaaaaca 8280 aaacaaaaaa ttagccgggt gtggtggcgg gtgcctgtag tcccagctac tcgagaagtt 8340 gaggcaggaa aatggcgtga acccaagagg cagagcttgc agtaagccga gatcacacca 8400 ctgcactcca gcctgggcga cagagcgaga ctccatctca aaaaaaagaa aaaaaaaaaa 8460 aaaaaaaaaa aaaggaaaac cattttaata gacttttatt tttagagctg ttttaagcta 8520 acagaaaaat tgcagaaatt gtatacagag ctcccccacc cccagtttct acaatgctta 8580 acatcctgta ttaatgtggt acacttgtta caattgatga accaatacta ataattatta 8640 ttaactaaaa ttcatagtta tacgagggtt cactctgtat ta 8682 // ID OW496048; SV 1; linear; genomic DNA; STD; HUM; 8682 BP. XX AC OW496048; XX PR Project:PRJEB52229; XX DT 28-APR-2022 (Rel. 144, Created) DT 29-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DRA gene for MHC class II antigen, allele DE HLA-DRA*01:01:01:NEW1 XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Turner R T.; RT ; RL Submitted (08-APR-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, The Royal Free Hospital, Pond Street, RL London, NW3 2QU, United Kingdom XX DR MD5; fd5015834bdbc63251d52c4b35eb0827. XX FH Key Location/Qualifiers FH FT source 1..8682 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="MZ070782" FT /db_xref="taxon:9606" FT CDS join(1449..1530,3944..4189,4681..4962,5252..5406) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH2618652.1" FT /translation="MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSG FT EFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNY FT TPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFL FT PREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL FT GLTVGLVGIIIGTIFIIKGVRKSNAAERRGPL" FT exon 1449..1530 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT intron 1531..3943 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT exon 3944..4189 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT intron 4190..4680 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT exon 4681..4962 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT intron 4963..5251 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT exon 5252..5406 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=4 XX SQ Sequence 8682 BP; 2534 A; 1810 C; 1847 G; 2491 T; 0 other; ctccctcact gccaggtcac tcttcatgga agtatttgta ttccagtcct ttctgtggaa 60 agaaattaac attctccttt tcataacact gtatcttcag aaacaagaga gtcgaagtct 120 cctaattttc aggactgtct atgttgaaca tcaaaatata ttctttagag cagatcttta 180 ataatcatat gacaagagaa aaactttcat aatcttatga catgagggaa ggaatattaa 240 agccgttctg tgggttatta tctctaacgt tcccaataga ataggctttg ccagctgggt 300 gcggtggctc atgcctgtaa tcccagcact ttgcgaggcc aaggcgggca aatcacgagg 360 tcaggagtct gagaccagcc tgaccaacat ggtgaaaccc cgtctctact aaaaatacaa 420 aaattagccg ggcatggtgg tgggcgcctg taatcccagc tactcaggag gctgaggcag 480 gagaatcgct tgaacccggg aggcggagat tacaatgagc tgagatcaca ccaccaactc 540 cagcttgggc gacagagcaa gactctgtct aaaaaaaaaa aaaaaaaaaa agaataggct 600 ttgcccacta tactctctca tattcattga cctgaatcct caaatgaggt gtgtccatta 660 gtcaactcca atctcttgtc atatataaga tggtagagat gagaagaagg tagctccttt 720 acagcccact atttccacta actactacct gtgtttcaag atacagcctt tcatccttct 780 ccagtgttga gagtgttgaa cctcagagtt tctcctctca ttttctctaa atgagataca 840 atgccagcca tcccaagctc ttggcctgag ttgatcatct tgaagtctag gactccaaga 900 agcatgaaag agcttcttta gtgaagctat gtcctcagta ctgccaaaat tcagacaatc 960 tccatggcct gacaatttac cttctatttg ggtaatttat tgtcccttac gcaaactctc 1020 caactgtcat tgcacagaca tatgatctgt atttagctct cactttaggt gtttccattg 1080 attctattct cactaatgtg cttcaggtat atccctgtct agaagtcaga ttggggttaa 1140 agagtctgtc cgtgattgac taacagtctt aaatacttga tttgttgttg ttgttgtcct 1200 gtttgtttaa gaactttact tctttatcca atgaacggag tatcttgtgt cctggaccct 1260 ttgcaagaac ccttccccta gcaacagatg cgtcatctca aaatattttt ctgattggcc 1320 aaagagtaat tgatttgcat tttaatggtc agactctatt acaccccaca ttctcttttc 1380 ttttattctt gtctgttctg cctcactccc gagctctact gactcccaaa agagcgccca 1440 agaagaaaat ggccataagt ggagtccctg tgctaggatt tttcatcata gctgtgctga 1500 tgagcgctca ggaatcatgg gctatcaaag gtaggtgctg agggaatgaa atctgggacg 1560 atagactacg aagcattgga gaaaagacct atggacattt ggaagataat gtgtggagtg 1620 aaagaatagt gtgacaggta ttatgtggtc tcgacagaaa gtataacaaa ttgtggtttg 1680 gtggagttct tccctcacca caaactgaag taagtcaaat ttggtttaga gggtcaaaac 1740 tgagttgtgt attgatgaat agcacggtcc tgctacaagc caaactgggg gtgggggtgg 1800 gggtggggga ggaagaatat tttctggcaa gcattaacaa gttatatttc tgggctttaa 1860 ttattctttc tggaaaatta gtaaaattaa aaactaaaaa ccacacatag ttttgctaga 1920 attaaatgaa aaaaaaagtt attagccctg ttcttatctg aatacatgat acagtagtta 1980 ttttttggag tgtaaatcct gtcggtatat attgagcaca tatattgtgt tgaagattac 2040 tagaaggaaa agtcatcaaa aagcaacaat ttaccccagg aaaaggggag ggaaggcatg 2100 ctgatatgag ttgcctcatg ggacagtgat agccattccc tgccttccca tctccatggt 2160 acagcagatc ttatatcatg ttaacttagt aatatttcca agagagtaga aaaataagga 2220 aggaaatggg gaatctgata ttattctctc tcatctccag agcaacattg gtgctgttgt 2280 aaagatgtac tgtagaaaag tattcttcac ccagcgtgac ccccacagaa ggtgtcaggt 2340 agacttgaaa taagcaaagt aataacccag ctcccatacc catagtggca attgtagatt 2400 tctattgccc caaaagagcc atacataggg atacttacct agaaagacag aggctcttcc 2460 cttggtttgt gaagaggcag ctagtatatt tgtgtgtgtt tgcatagatg caaacggtaa 2520 ataaattcct aggtttatca atacacagtc aaacattaaa atctctcatc ttggctgggc 2580 acggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 2640 tcaagagatc gagaccgtcc tgggcaacat ggtgaaaccc cgtctctact aaaaatacaa 2700 aaaattagct gggtatggtg gcacacgcct gtagtcccag ctactcggga ggctgaggca 2760 ggaggattgc ttgagcccgg gaggcggagg ttgcagtgag ctgagatggt gccactgcac 2820 tccagcctgg cgatagagca agactccgtc tcaaacaacc aaaccaaaac aaaacaaaat 2880 atctcacctt atctttgaag actaaggaaa aaaaaaatct cccactcatc gatacactcc 2940 acagaggcag catactctcc cagtgtagct ttctcttttc atgttcatta ttcccttggt 3000 gttggttatt ctcaatgtca atcgtaacag aacatcttcc ataataacag tcccaattta 3060 aggagcatta agataaaagg tggaattgcc aaggtcaatc cagacgagaa ccttctcata 3120 gaggtaacca ccgtgtgggt ttggatgctg ggaagcaggg ggactatgac gctacaaggt 3180 ctcagtctta atttttggag tacttcagtc cccaggtata ttttccatag atttggccct 3240 taaataaaaa gaagcttctg actctaaaat gtaaacagtg cttgttacag tcttgttgat 3300 atattaagaa attactcacc ttatctcatt taatcttaaa aacaaacccc tgacaggatc 3360 aaaaccacag cagggctaca taataggaaa actatacata aataggtaga ataatctgct 3420 caggatcact aggtaagttg ctgaataaga attcaagatg tttttgatcc cagagtttaa 3480 aacccaacct ttcaaacagt gtttccttct tcttagagta caatgttctg agaaagagat 3540 cctctggaat tctggcctaa gtgtatttaa tgcccgggta aagaaagtga gagaacattt 3600 ctctttaggg gctgctgctg gatttctaaa aagaaaataa tttctcagct agtaacatgg 3660 agccaaacaa cagcttcaca agactctggg ttctttagcc ctcatctcct tcaatccacc 3720 ctctttataa ccagtccttc ttgtttttcc cctcccagct ttgttcagca gcatgccctt 3780 cacccagacc ttgtcttgtc actcatccct actcgccatc attctttcat tcctcttggc 3840 ccaatctctc tccaccactt cctgcctaca tgtatgtagg ttattcattt ccctctcttg 3900 attcccccca cccaactctc tttctccatt tcttgccttt cagaagaaca tgtgatcatc 3960 caggccgagt tctatctgaa tcctgaccaa tcaggcgagt ttatgtttga ctttgatggt 4020 gatgagattt tccatgtgga tatggcaaag aaggagacgg tctggcggct tgaagaattt 4080 ggacgatttg ccagctttga ggctcaaggt gcattggcca acatagctgt ggacaaagcc 4140 aacctggaaa tcatgacaaa gcgctccaac tatactccga tcaccaatgg tacctccctc 4200 tctgctgcac tcctggacat gggaatccat agtttgaaag tagttgcttc agctctttgt 4260 gttagattat tgtaactgat tttccctcca agggcctaac cttgccatta acaagcccca 4320 aattctcatg ccagaggtct gagaacttta tgggtttgat cctatcttgt tgtgctcaag 4380 tcttgtctct gtcatccatg gtctcctacg aagtcattgc cctaagttca tgctagggga 4440 gccagaaggg aagtccttgg atatcttata cctcaatatt ggctcaattt cttggggagg 4500 gggtgctgtc agagattgtt atctgaggat gtgacataga tttctcaggg cacaatttca 4560 actacttttt cagctttagg gtttttagat acgtttgtac cacaattgag catgggaggg 4620 agaggggtga gcctaagcag tgatggctga tttctgtcac gtctgtcatg tgtcccccag 4680 tacctccaga ggtaactgtg ctcacgaaca gccctgtgga actgagagag cccaacgtcc 4740 tcatctgttt catcgacaag ttcaccccac cagtggtcaa tgtcacgtgg cttcgaaatg 4800 gaaaacctgt caccacagga gtgtcagaga cagtcttcct gcccagggaa gaccaccttt 4860 tccgcaagtt ccactatctc cccttcctgc cctcaactga ggacgtttac gactgcaggg 4920 tggagcactg gggcttggat gagcctcttc tcaagcactg gggtatggac caacactcaa 4980 tctcctttat ttcaaggttt cctcctatga tgcttgtgtg aaactcggtg ttctaactgt 5040 ttcataatat ctgctacaat taatataact gtcttctcct actatccagc ttcctccttt 5100 ttttaatctg taattctctc aatacatcat tctgtcttcc tcttctttaa tctatgaata 5160 acttttctct ttattaagaa ccctacattt gattctgagt gttacttctt cccacactca 5220 ttaccatgta ctctgcctta tctcccccca gagtttgatg ctccaagccc tctcccagag 5280 actacagaga acgtggtgtg tgccctgggc ctgactgtgg gtctggtggg catcattatt 5340 gggaccatct tcatcatcaa gggagtgcgc aaaagcaatg cagcagaacg cagggggcct 5400 ctgtaaggca catggaggtg agttaggtgt ggtcagagga agacatatat ggagatatct 5460 gagggaggaa aacagggtgg ggaaaggaaa tgtaatgcat ttaagagaca aggtaggaac 5520 agatgtggct cttgatttct ctttgctaga atgaatcaga cattggtatc atctggtatc 5580 ccaaagcttc agggtctgtc atccctttct atagacgggc accttgatca cggctccagt 5640 cttagaaatc atctccagta cctaaaacca ttgtttcaca ttagaatact gagtctaggg 5700 atctagaaaa tacattagaa tatggagtct agggatctag aaaatactga gtctagggat 5760 ctagaaaaat aagcctcaag atttgggcac atcctagctt gtatttcctg gggcaggtca 5820 tcagttcaga agcatttcca gatcctggct cctttcaggt tagggtcaat tcattgcatg 5880 aaatgggaat ctcttagagg ccaatgcctg cttttgcttc tttagtctca aatgtagtat 5940 gagaaactct aaaaaaaggt aaagcatggt tgcttattat gttcagttgg agagtaggaa 6000 ctaactgtat acagttagtt catgttggaa aggttagatg aacattgaaa gaattttgca 6060 aagtcaaagg attaagagag aagaggaagg aatctgaagc aaggagctca aaacggatct 6120 taaattcctt ggtaactatg tgtgtcttgc tataggtgat ggtgtttctt agagagaaga 6180 tcactgaaga aacttctgct ttaatgactt tacaaagctg gcaatattac aatccttgac 6240 ctcagtgaaa gcagtcatct tcagcgtttt ccagccctat agccacccca agtgtggtta 6300 tgcctcctcg attgctccgt actctaacat ctagctggct tccctgtcta ttgccttttc 6360 ctgtatctat tttcctctat ttcctatcat tttattatca ccatgcaatg cctctggaat 6420 aaaacataca ggagtctgtc tctgctatgg aatgccccat ggggcatctc ttgtgtactt 6480 attgtttaag gtttcctcaa actgtgattt ttctgaacac aataaactat tttgatgatc 6540 ttgggtggaa tttttggtgt ttaagccagt tctttgggtg gcggtggggg gtggggagtc 6600 ggtcctgggg aatatatgtg atcctttccc ggtaaaatat ctgaatgttg aatttatctt 6660 ataaattcta gaattcatca gacatatccc ggttcatttg ggcttggtct cattttgtgc 6720 atctgcaggc aaccctcttg ttgtggtcta gtcctcatca ggaaaaccta aagtggggtt 6780 ggtttgttgg gagatctcta ctgagcaatg atataactct gtcttcagta gagtgaatct 6840 gaaaccccaa ggtatggatc tcagaatgca tgggatagag gggagcagat ggggttagag 6900 tggggagaag gaagacagaa gaatccataa acattgcagg atttacatat caacatcgtt 6960 cattccagat ttaatgagca aagaggttgg acactgaaga ctggccttac ccattctgtt 7020 agacatagtc tcagatgcct attttattac cgagagagta gtctgactga ttcttgaaac 7080 caccttatat ttgaagatgt gtctttgagt ggaaaagctg agtgaaattt ggggttgggg 7140 agaaagatat gacattaaga tgagaggaag gaatatttga aacacaatga actgttgctc 7200 atttgtctat aaaactatga cttgatattt atctctaaaa tagtttctag aacctgccat 7260 aaaccactaa gataaactat tcatgatagt gtggtagact gcaaataaat gctgttgaaa 7320 tgagttaggc ttgggtttca tcttggctgt atcatttact agctatgttt tcactggtat 7380 cttacttaac ttagcctcac attactcatg aaaatactgg tgttaatttt tactacattg 7440 aattaatatc agaattaaaa ggaaaacgca agcaaagtaa ttagatacat gcttagtgat 7500 aataaaatat tgcaaaaaat tatacattct gttgtttttc tcaaaatttc tatagactga 7560 tgataaaaat ctaagagaag ctaaacaaaa caaggataaa ccaaagcatc atgacattct 7620 aagccttact aataaataag aagtttctcg gctgggcacg gtggctcacg cctgtaatcc 7680 agcactttgg gaggccgagg tgggcggatc acaaggtcag gaaatcaaga ccatcctggc 7740 caacatggtg aaaccccatc tctactaaaa atacaaaaat tagccaggcg tggtgatagg 7800 cgcctgtaat cccagctact ctggaggttg aggcaggaga atctcttgaa tccgggaggc 7860 agaggttgca gtgagccgag atcgcaccac tgcgctcctg cctggcaaca gactgagact 7920 ccgtctcaaa aaaaaaaaaa aaaaaaagtt tctctactgt tggttcagag aatcaaagca 7980 gaatcttgag actactgatg gtagaatagg tacgagtgtc tttcttacat gactacaaac 8040 tttattataa aataaatagc ttaacacaga gaatacacta aaacttagac aagcatggat 8100 taagaaagca aaaagtaaac ccatatacta ccatgtaaga aaaccatttt tggccaggtg 8160 cggtggctca cgcctgtaat cccagcactt tgggaggccg aggcgggcgg atcacgaggt 8220 caggagatcg agaccatcct ggctaacatg gtgaaacccc gtctctacta aaaaaaaaca 8280 aaacaaaaaa ttagccgggt gtggtggcgg gtgcctgtag tcccagctac tcgagaagtt 8340 gaggcaggaa aatggcgtga acccaagagg cagagcttgc agtaagccga gatcacacca 8400 ctgcactcca gcctgggcga cagagcgaga ctccatctca aaaaaaagaa aaaaaaaaaa 8460 aaaaaaaaaa aaaggaaaac cattttaata gacttttatt tttagagctg ttttaagcta 8520 acagaaaaat tgcagaaatt gtatacagag ctcccccacc cccagtttct acaatgctta 8580 acatcctgta ttaatgtggt acacttgtta caattgatga accaatacta ataattatta 8640 ttaactaaaa ttcatagtta tacgagggtt cactctgtat ta 8682 // ID OW496049; SV 1; linear; genomic DNA; STD; HUM; 8682 BP. XX AC OW496049; XX PR Project:PRJEB52229; XX DT 28-APR-2022 (Rel. 144, Created) DT 29-APR-2022 (Rel. 144, Last updated, Version 1) XX DE Homo sapiens HLA-DRA gene for MHC class II antigen, allele DE HLA-DRA*01:01:01:NEW1 XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Turner R T.; RT ; RL Submitted (08-APR-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, The Royal Free Hospital, Pond Street, RL London, NW3 2QU, United Kingdom XX DR MD5; fd5015834bdbc63251d52c4b35eb0827. XX FH Key Location/Qualifiers FH FT source 1..8682 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="NA01018" FT /db_xref="taxon:9606" FT CDS join(1449..1530,3944..4189,4681..4962,5252..5406) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH2618653.1" FT /translation="MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSG FT EFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNY FT TPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFL FT PREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL FT GLTVGLVGIIIGTIFIIKGVRKSNAAERRGPL" FT exon 1449..1530 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT intron 1531..3943 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=1 FT exon 3944..4189 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT intron 4190..4680 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=2 FT exon 4681..4962 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT intron 4963..5251 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=3 FT exon 5252..5406 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW1" FT /number=4 XX SQ Sequence 8682 BP; 2534 A; 1810 C; 1847 G; 2491 T; 0 other; ctccctcact gccaggtcac tcttcatgga agtatttgta ttccagtcct ttctgtggaa 60 agaaattaac attctccttt tcataacact gtatcttcag aaacaagaga gtcgaagtct 120 cctaattttc aggactgtct atgttgaaca tcaaaatata ttctttagag cagatcttta 180 ataatcatat gacaagagaa aaactttcat aatcttatga catgagggaa ggaatattaa 240 agccgttctg tgggttatta tctctaacgt tcccaataga ataggctttg ccagctgggt 300 gcggtggctc atgcctgtaa tcccagcact ttgcgaggcc aaggcgggca aatcacgagg 360 tcaggagtct gagaccagcc tgaccaacat ggtgaaaccc cgtctctact aaaaatacaa 420 aaattagccg ggcatggtgg tgggcgcctg taatcccagc tactcaggag gctgaggcag 480 gagaatcgct tgaacccggg aggcggagat tacaatgagc tgagatcaca ccaccaactc 540 cagcttgggc gacagagcaa gactctgtct aaaaaaaaaa aaaaaaaaaa agaataggct 600 ttgcccacta tactctctca tattcattga cctgaatcct caaatgaggt gtgtccatta 660 gtcaactcca atctcttgtc atatataaga tggtagagat gagaagaagg tagctccttt 720 acagcccact atttccacta actactacct gtgtttcaag atacagcctt tcatccttct 780 ccagtgttga gagtgttgaa cctcagagtt tctcctctca ttttctctaa atgagataca 840 atgccagcca tcccaagctc ttggcctgag ttgatcatct tgaagtctag gactccaaga 900 agcatgaaag agcttcttta gtgaagctat gtcctcagta ctgccaaaat tcagacaatc 960 tccatggcct gacaatttac cttctatttg ggtaatttat tgtcccttac gcaaactctc 1020 caactgtcat tgcacagaca tatgatctgt atttagctct cactttaggt gtttccattg 1080 attctattct cactaatgtg cttcaggtat atccctgtct agaagtcaga ttggggttaa 1140 agagtctgtc cgtgattgac taacagtctt aaatacttga tttgttgttg ttgttgtcct 1200 gtttgtttaa gaactttact tctttatcca atgaacggag tatcttgtgt cctggaccct 1260 ttgcaagaac ccttccccta gcaacagatg cgtcatctca aaatattttt ctgattggcc 1320 aaagagtaat tgatttgcat tttaatggtc agactctatt acaccccaca ttctcttttc 1380 ttttattctt gtctgttctg cctcactccc gagctctact gactcccaaa agagcgccca 1440 agaagaaaat ggccataagt ggagtccctg tgctaggatt tttcatcata gctgtgctga 1500 tgagcgctca ggaatcatgg gctatcaaag gtaggtgctg agggaatgaa atctgggacg 1560 atagactacg aagcattgga gaaaagacct atggacattt ggaagataat gtgtggagtg 1620 aaagaatagt gtgacaggta ttatgtggtc tcgacagaaa gtataacaaa ttgtggtttg 1680 gtggagttct tccctcacca caaactgaag taagtcaaat ttggtttaga gggtcaaaac 1740 tgagttgtgt attgatgaat agcacggtcc tgctacaagc caaactgggg gtgggggtgg 1800 gggtggggga ggaagaatat tttctggcaa gcattaacaa gttatatttc tgggctttaa 1860 ttattctttc tggaaaatta gtaaaattaa aaactaaaaa ccacacatag ttttgctaga 1920 attaaatgaa aaaaaaagtt attagccctg ttcttatctg aatacatgat acagtagtta 1980 ttttttggag tgtaaatcct gtcggtatat attgagcaca tatattgtgt tgaagattac 2040 tagaaggaaa agtcatcaaa aagcaacaat ttaccccagg aaaaggggag ggaaggcatg 2100 ctgatatgag ttgcctcatg ggacagtgat agccattccc tgccttccca tctccatggt 2160 acagcagatc ttatatcatg ttaacttagt aatatttcca agagagtaga aaaataagga 2220 aggaaatggg gaatctgata ttattctctc tcatctccag agcaacattg gtgctgttgt 2280 aaagatgtac tgtagaaaag tattcttcac ccagcgtgac ccccacagaa ggtgtcaggt 2340 agacttgaaa taagcaaagt aataacccag ctcccatacc catagtggca attgtagatt 2400 tctattgccc caaaagagcc atacataggg atacttacct agaaagacag aggctcttcc 2460 cttggtttgt gaagaggcag ctagtatatt tgtgtgtgtt tgcatagatg caaacggtaa 2520 ataaattcct aggtttatca atacacagtc aaacattaaa atctctcatc ttggctgggc 2580 acggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 2640 tcaagagatc gagaccgtcc tgggcaacat ggtgaaaccc cgtctctact aaaaatacaa 2700 aaaattagct gggtatggtg gcacacgcct gtagtcccag ctactcggga ggctgaggca 2760 ggaggattgc ttgagcccgg gaggcggagg ttgcagtgag ctgagatggt gccactgcac 2820 tccagcctgg cgatagagca agactccgtc tcaaacaacc aaaccaaaac aaaacaaaat 2880 atctcacctt atctttgaag actaaggaaa aaaaaaatct cccactcatc gatacactcc 2940 acagaggcag catactctcc cagtgtagct ttctcttttc atgttcatta ttcccttggt 3000 gttggttatt ctcaatgtca atcgtaacag aacatcttcc ataataacag tcccaattta 3060 aggagcatta agataaaagg tggaattgcc aaggtcaatc cagacgagaa ccttctcata 3120 gaggtaacca ccgtgtgggt ttggatgctg ggaagcaggg ggactatgac gctacaaggt 3180 ctcagtctta atttttggag tacttcagtc cccaggtata ttttccatag atttggccct 3240 taaataaaaa gaagcttctg actctaaaat gtaaacagtg cttgttacag tcttgttgat 3300 atattaagaa attactcacc ttatctcatt taatcttaaa aacaaacccc tgacaggatc 3360 aaaaccacag cagggctaca taataggaaa actatacata aataggtaga ataatctgct 3420 caggatcact aggtaagttg ctgaataaga attcaagatg tttttgatcc cagagtttaa 3480 aacccaacct ttcaaacagt gtttccttct tcttagagta caatgttctg agaaagagat 3540 cctctggaat tctggcctaa gtgtatttaa tgcccgggta aagaaagtga gagaacattt 3600 ctctttaggg gctgctgctg gatttctaaa aagaaaataa tttctcagct agtaacatgg 3660 agccaaacaa cagcttcaca agactctggg ttctttagcc ctcatctcct tcaatccacc 3720 ctctttataa ccagtccttc ttgtttttcc cctcccagct ttgttcagca gcatgccctt 3780 cacccagacc ttgtcttgtc actcatccct actcgccatc attctttcat tcctcttggc 3840 ccaatctctc tccaccactt cctgcctaca tgtatgtagg ttattcattt ccctctcttg 3900 attcccccca cccaactctc tttctccatt tcttgccttt cagaagaaca tgtgatcatc 3960 caggccgagt tctatctgaa tcctgaccaa tcaggcgagt ttatgtttga ctttgatggt 4020 gatgagattt tccatgtgga tatggcaaag aaggagacgg tctggcggct tgaagaattt 4080 ggacgatttg ccagctttga ggctcaaggt gcattggcca acatagctgt ggacaaagcc 4140 aacctggaaa tcatgacaaa gcgctccaac tatactccga tcaccaatgg tacctccctc 4200 tctgctgcac tcctggacat gggaatccat agtttgaaag tagttgcttc agctctttgt 4260 gttagattat tgtaactgat tttccctcca agggcctaac cttgccatta acaagcccca 4320 aattctcatg ccagaggtct gagaacttta tgggtttgat cctatcttgt tgtgctcaag 4380 tcttgtctct gtcatccatg gtctcctacg aagtcattgc cctaagttca tgctagggga 4440 gccagaaggg aagtccttgg atatcttata cctcaatatt ggctcaattt cttggggagg 4500 gggtgctgtc agagattgtt atctgaggat gtgacataga tttctcaggg cacaatttca 4560 actacttttt cagctttagg gtttttagat acgtttgtac cacaattgag catgggaggg 4620 agaggggtga gcctaagcag tgatggctga tttctgtcac gtctgtcatg tgtcccccag 4680 tacctccaga ggtaactgtg ctcacgaaca gccctgtgga actgagagag cccaacgtcc 4740 tcatctgttt catcgacaag ttcaccccac cagtggtcaa tgtcacgtgg cttcgaaatg 4800 gaaaacctgt caccacagga gtgtcagaga cagtcttcct gcccagggaa gaccaccttt 4860 tccgcaagtt ccactatctc cccttcctgc cctcaactga ggacgtttac gactgcaggg 4920 tggagcactg gggcttggat gagcctcttc tcaagcactg gggtatggac caacactcaa 4980 tctcctttat ttcaaggttt cctcctatga tgcttgtgtg aaactcggtg ttctaactgt 5040 ttcataatat ctgctacaat taatataact gtcttctcct actatccagc ttcctccttt 5100 ttttaatctg taattctctc aatacatcat tctgtcttcc tcttctttaa tctatgaata 5160 acttttctct ttattaagaa ccctacattt gattctgagt gttacttctt cccacactca 5220 ttaccatgta ctctgcctta tctcccccca gagtttgatg ctccaagccc tctcccagag 5280 actacagaga acgtggtgtg tgccctgggc ctgactgtgg gtctggtggg catcattatt 5340 gggaccatct tcatcatcaa gggagtgcgc aaaagcaatg cagcagaacg cagggggcct 5400 ctgtaaggca catggaggtg agttaggtgt ggtcagagga agacatatat ggagatatct 5460 gagggaggaa aacagggtgg ggaaaggaaa tgtaatgcat ttaagagaca aggtaggaac 5520 agatgtggct cttgatttct ctttgctaga atgaatcaga cattggtatc atctggtatc 5580 ccaaagcttc agggtctgtc atccctttct atagacgggc accttgatca cggctccagt 5640 cttagaaatc atctccagta cctaaaacca ttgtttcaca ttagaatact gagtctaggg 5700 atctagaaaa tacattagaa tatggagtct agggatctag aaaatactga gtctagggat 5760 ctagaaaaat aagcctcaag atttgggcac atcctagctt gtatttcctg gggcaggtca 5820 tcagttcaga agcatttcca gatcctggct cctttcaggt tagggtcaat tcattgcatg 5880 aaatgggaat ctcttagagg ccaatgcctg cttttgcttc tttagtctca aatgtagtat 5940 gagaaactct aaaaaaaggt aaagcatggt tgcttattat gttcagttgg agagtaggaa 6000 ctaactgtat acagttagtt catgttggaa aggttagatg aacattgaaa gaattttgca 6060 aagtcaaagg attaagagag aagaggaagg aatctgaagc aaggagctca aaacggatct 6120 taaattcctt ggtaactatg tgtgtcttgc tataggtgat ggtgtttctt agagagaaga 6180 tcactgaaga aacttctgct ttaatgactt tacaaagctg gcaatattac aatccttgac 6240 ctcagtgaaa gcagtcatct tcagcgtttt ccagccctat agccacccca agtgtggtta 6300 tgcctcctcg attgctccgt actctaacat ctagctggct tccctgtcta ttgccttttc 6360 ctgtatctat tttcctctat ttcctatcat tttattatca ccatgcaatg cctctggaat 6420 aaaacataca ggagtctgtc tctgctatgg aatgccccat ggggcatctc ttgtgtactt 6480 attgtttaag gtttcctcaa actgtgattt ttctgaacac aataaactat tttgatgatc 6540 ttgggtggaa tttttggtgt ttaagccagt tctttgggtg gcggtggggg gtggggagtc 6600 ggtcctgggg aatatatgtg atcctttccc ggtaaaatat ctgaatgttg aatttatctt 6660 ataaattcta gaattcatca gacatatccc ggttcatttg ggcttggtct cattttgtgc 6720 atctgcaggc aaccctcttg ttgtggtcta gtcctcatca ggaaaaccta aagtggggtt 6780 ggtttgttgg gagatctcta ctgagcaatg atataactct gtcttcagta gagtgaatct 6840 gaaaccccaa ggtatggatc tcagaatgca tgggatagag gggagcagat ggggttagag 6900 tggggagaag gaagacagaa gaatccataa acattgcagg atttacatat caacatcgtt 6960 cattccagat ttaatgagca aagaggttgg acactgaaga ctggccttac ccattctgtt 7020 agacatagtc tcagatgcct attttattac cgagagagta gtctgactga ttcttgaaac 7080 caccttatat ttgaagatgt gtctttgagt ggaaaagctg agtgaaattt ggggttgggg 7140 agaaagatat gacattaaga tgagaggaag gaatatttga aacacaatga actgttgctc 7200 atttgtctat aaaactatga cttgatattt atctctaaaa tagtttctag aacctgccat 7260 aaaccactaa gataaactat tcatgatagt gtggtagact gcaaataaat gctgttgaaa 7320 tgagttaggc ttgggtttca tcttggctgt atcatttact agctatgttt tcactggtat 7380 cttacttaac ttagcctcac attactcatg aaaatactgg tgttaatttt tactacattg 7440 aattaatatc agaattaaaa ggaaaacgca agcaaagtaa ttagatacat gcttagtgat 7500 aataaaatat tgcaaaaaat tatacattct gttgtttttc tcaaaatttc tatagactga 7560 tgataaaaat ctaagagaag ctaaacaaaa caaggataaa ccaaagcatc atgacattct 7620 aagccttact aataaataag aagtttctcg gctgggcacg gtggctcacg cctgtaatcc 7680 agcactttgg gaggccgagg tgggcggatc acaaggtcag gaaatcaaga ccatcctggc 7740 caacatggtg aaaccccatc tctactaaaa atacaaaaat tagccaggcg tggtgatagg 7800 cgcctgtaat cccagctact ctggaggttg aggcaggaga atctcttgaa tccgggaggc 7860 agaggttgca gtgagccgag atcgcaccac tgcgctcctg cctggcaaca gactgagact 7920 ccgtctcaaa aaaaaaaaaa aaaaaaagtt tctctactgt tggttcagag aatcaaagca 7980 gaatcttgag actactgatg gtagaatagg tacgagtgtc tttcttacat gactacaaac 8040 tttattataa aataaatagc ttaacacaga gaatacacta aaacttagac aagcatggat 8100 taagaaagca aaaagtaaac ccatatacta ccatgtaaga aaaccatttt tggccaggtg 8160 cggtggctca cgcctgtaat cccagcactt tgggaggccg aggcgggcgg atcacgaggt 8220 caggagatcg agaccatcct ggctaacatg gtgaaacccc gtctctacta aaaaaaaaca 8280 aaacaaaaaa ttagccgggt gtggtggcgg gtgcctgtag tcccagctac tcgagaagtt 8340 gaggcaggaa aatggcgtga acccaagagg cagagcttgc agtaagccga gatcacacca 8400 ctgcactcca gcctgggcga cagagcgaga ctccatctca aaaaaaagaa aaaaaaaaaa 8460 aaaaaaaaaa aaaggaaaac cattttaata gacttttatt tttagagctg ttttaagcta 8520 acagaaaaat tgcagaaatt gtatacagag ctcccccacc cccagtttct acaatgctta 8580 acatcctgta ttaatgtggt acacttgtta caattgatga accaatacta ataattatta 8640 ttaactaaaa ttcatagtta tacgagggtt cactctgtat ta 8682 // ID OX111307; SV 1; linear; genomic DNA; STD; HUM; 8684 BP. XX AC OX111307; XX PR Project:PRJEB53805; XX DT 07-JUL-2022 (Rel. 144, Created) DT 05-AUG-2022 (Rel. 144, Last updated, Version 2) XX DE Homo sapiens HLA-DRA gene for MHC class II antigen, allele DE HLA-DRA*01:01:01:NEW XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Turner R T.; RT ; RL Submitted (23-JUN-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, The Royal Free Hospital, Pond Street, RL London, NW3 2QU, United Kingdom XX DR MD5; ac140ff3912cde1ecdba70eb60ba5fd9. XX FH Key Location/Qualifiers FH FT source 1..8684 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="AN300324" FT /db_xref="taxon:9606" FT CDS join(1449..1530,3944..4189,4681..4962,5252..5406) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH8161913.1" FT /translation="MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSG FT EFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNY FT TPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFL FT PREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL FT GLTVGLVGIIIGTIFIIKGVRKSNAAERRGPL" FT exon 1449..1530 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=1 FT intron 1531..3943 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=1 FT exon 3944..4189 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=2 FT intron 4190..4680 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=2 FT exon 4681..4962 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=3 FT intron 4963..5251 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=3 FT exon 5252..5406 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=4 XX SQ Sequence 8684 BP; 2536 A; 1810 C; 1847 G; 2491 T; 0 other; ctccctcact gccaggtcac tcttcatgga agtatttgta ttccagtcct ttctgtggaa 60 agaaattaac attctccttt tcataacact gtatcttcag aaacaagaga gtcgaagtct 120 cctaattttc aggactgtct atgttgaaca tcaaaatata ttctttagag cagatcttta 180 ataatcatat gacaagagaa aaactttcat aatcttatga catgagggaa ggaatattaa 240 agccgttctg tgggttatta tctctaacgt tcccaataga ataggctttg ccagctgggt 300 gcggtggctc atgcctgtaa tcccagcact ttgcgaggcc aaggcgggca aatcacgagg 360 tcaggagtct gagaccagcc tgaccaacat ggtgaaaccc cgtctctact aaaaatacaa 420 aaattagccg ggcatggtgg tgggcgcctg taatcccagc tactcaggag gctgaggcag 480 gagaatcgct tgaacccggg aggcggagat tacaatgagc tgagatcaca ccaccaactc 540 cagcttgggc gacagagcaa gactctgtct aaaaaaaaaa aaaaaaaaaa agaataggct 600 ttgcccacta tactctctca tattcattga cctgaatcct caaatgaggt gtgtccatta 660 gtcaactcca atctcttgtc atatataaga tggtagagat gagaagaagg tagctccttt 720 acagcccact atttccacta actactacct gtgtttcaag atacagcctt tcatccttct 780 ccagtgttga gagtgttgaa cctcagagtt tctcctctca ttttctctaa atgagataca 840 atgccagcca tcccaagctc ttggcctgag ttgatcatct tgaagtctag gactccaaga 900 agcatgaaag agcttcttta gtgaagctat gtcctcagta ctgccaaaat tcagacaatc 960 tccatggcct gacaatttac cttctatttg ggtaatttat tgtcccttac gcaaactctc 1020 caactgtcat tgcacagaca tatgatctgt atttagctct cactttaggt gtttccattg 1080 attctattct cactaatgtg cttcaggtat atccctgtct agaagtcaga ttggggttaa 1140 agagtctgtc cgtgattgac taacagtctt aaatacttga tttgttgttg ttgttgtcct 1200 gtttgtttaa gaactttact tctttatcca atgaacggag tatcttgtgt cctggaccct 1260 ttgcaagaac ccttccccta gcaacagatg cgtcatctca aaatattttt ctgattggcc 1320 aaagagtaat tgatttgcat tttaatggtc agactctatt acaccccaca ttctcttttc 1380 ttttattctt gtctgttctg cctcactccc gagctctact gactcccaaa agagcgccca 1440 agaagaaaat ggccataagt ggagtccctg tgctaggatt tttcatcata gctgtgctga 1500 tgagcgctca ggaatcatgg gctatcaaag gtaggtgctg agggaatgaa atctgggacg 1560 atagactacg aagcattgga gaaaagacct atggacattt ggaagataat gtgtggagtg 1620 aaagaatagt gtgacaggta ttatgtggtc tcgacagaaa gtataacaaa ttgtggtttg 1680 gtggagttct tccctcacca caaactgaag taagtcaaat ttggtttaga gggtcaaaac 1740 tgagttgtgt attgatgaat agcacggtcc tgctacaagc caaactgggg gtgggggtgg 1800 gggtggggga ggaagaatat tttctggcaa gcattaacaa gttatatttc tgggctttaa 1860 ttattctttc tggaaaatta gtaaaattaa aaactaaaaa ccacacatag ttttgctaga 1920 attaaatgaa aaaaaaagtt attagccctg ttcttatctg aatacatgat acagtagtta 1980 ttttttggag tgtaaatcct gtcggtatat attgagcaca tatattgtgt tgaagattac 2040 tagaaggaaa agtcatcaaa aagcaacaat ttaccccagg aaaaggggag ggaaggcatg 2100 ctgatatgag ttgcctcatg ggacagtgat agccattccc tgccttccca tctccatggt 2160 acagcagatc ttatatcatg ttaacttagt aatatttcca agagagtaga aaaataagga 2220 aggaaatggg gaatctgata ttattctctc tcatctccag agcaacattg gtgctgttgt 2280 aaagatgtac tgtagaaaag tattcttcac ccagcgtgac ccccacagaa ggtgtcaggt 2340 agacttgaaa taagcaaagt aataacccag ctcccatacc catagtggca attgtagatt 2400 tctattgccc caaaagagcc atacataggg atacttacct agaaagacag aggctcttcc 2460 cttggtttgt gaagaggcag ctagtatatt tgtgtgtgtt tgcatagatg caaacggtaa 2520 ataaattcct aggtttatca atacacagtc aaacattaaa atctctcatc ttggctgggc 2580 acggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 2640 tcaagagatc gagaccgtcc tgggcaacat ggtgaaaccc cgtctctact aaaaatacaa 2700 aaaattagct gggtatggtg gcacacgcct gtagtcccag ctactcggga ggctgaggca 2760 ggaggattgc ttgagcccgg gaggcggagg ttgcagtgag ctgagatggt gccactgcac 2820 tccagcctgg cgatagagca agactccgtc tcaaacaacc aaaccaaaac aaaacaaaat 2880 atctcacctt atctttgaag actaaggaaa aaaaaaatct cccactcatc gatacactcc 2940 acagaggcag catactctcc cagtgtagct ttctcttttc atgttcatta ttcccttggt 3000 gttggttatt ctcaatgtca atcgtaacag aacatcttcc ataataacag tcccaattta 3060 aggagcatta agataaaagg tggaattgcc aaggtcaatc cagacgagaa ccttctcata 3120 gaggtaacca ccgtgtgggt ttggatgctg ggaagcaggg ggactatgac gctacaaggt 3180 ctcagtctta atttttggag tacttcagtc cccaggtata ttttccatag atttggccct 3240 taaataaaaa gaagcttctg actctaaaat gtaaacagtg cttgttacag tcttgttgat 3300 atattaagaa attactcacc ttatctcatt taatcttaaa aacaaacccc tgacaggatc 3360 aaaaccacag cagggctaca taataggaaa actatacata aataggtaga ataatctgct 3420 caggatcact aggtaagttg ctgaataaga attcaagatg tttttgatcc cagagtttaa 3480 aacccaacct ttcaaacagt gtttccttct tcttagagta caatgttctg agaaagagat 3540 cctctggaat tctggcctaa gtgtatttaa tgcccgggta aagaaagtga gagaacattt 3600 ctctttaggg gctgctgctg gatttctaaa aagaaaataa tttctcagct agtaacatgg 3660 agccaaacaa cagcttcaca agactctggg ttctttagcc ctcatctcct tcaatccacc 3720 ctctttataa ccagtccttc ttgtttttcc cctcccagct ttgttcagca gcatgccctt 3780 cacccagacc ttgtcttgtc actcatccct actcgccatc attctttcat tcctcttggc 3840 ccaatctctc tccaccactt cctgcctaca tgtatgtagg ttattcattt ccctctcttg 3900 attcccccca cccaactctc tttctccatt tcttgccttt cagaagaaca tgtgatcatc 3960 caggccgagt tctatctgaa tcctgaccaa tcaggcgagt ttatgtttga ctttgatggt 4020 gatgagattt tccatgtgga tatggcaaag aaggagacgg tctggcggct tgaagaattt 4080 ggacgatttg ccagctttga ggctcaaggt gcattggcca acatagctgt ggacaaagcc 4140 aacctggaaa tcatgacaaa gcgctccaac tatactccga tcaccaatgg tacctccctc 4200 tctgctgcac tcctggacat gggaatccat agtttgaaag tagttgcttc agctctttgt 4260 gttagattat tgtaactgat tttccctcca agggcctaac cttgccatta acaagcccca 4320 aattctcatg ccagaggtct gagaacttta tgggtttgat cctatcttgt tgtgctcaag 4380 tcttgtctct gtcatccatg gtctcctacg aagtcattgc cctaagttca tgctagggga 4440 gccagaaggg aagtccttgg atatcttata cctcaatatt ggctcaattt cttggggagg 4500 gggtgctgtc agagattgtt atctgaggat gtgacataga tttctcaggg cacaatttca 4560 actacttttt cagctttagg gtttttagat acgtttgtac cacaattgag catgggaggg 4620 agaggggtga gcctaagcag tgatggctga tttctgtcac gtctgtcatg tgtcccccag 4680 tacctccaga ggtaactgtg ctcacgaaca gccctgtgga actgagagag cccaacgtcc 4740 tcatctgttt catcgacaag ttcaccccac cagtggtcaa tgtcacgtgg cttcgaaatg 4800 gaaaacctgt caccacagga gtgtcagaga cagtcttcct gcccagggaa gaccaccttt 4860 tccgcaagtt ccactatctc cccttcctgc cctcaactga ggacgtttac gactgcaggg 4920 tggagcactg gggcttggat gagcctcttc tcaagcactg gggtatggac caacactcaa 4980 tctcctttat ttcaaggttt cctcctatga tgcttgtgtg aaactcggtg ttctaactgt 5040 ttcataatat ctgctacaat taatataact gtcttctcct actatccagc ttcctccttt 5100 ttttaatctg taattctctc aatacatcat tctgtcttcc tcttctttaa tctatgaata 5160 acttttctct ttattaagaa ccctacattt gattctgagt gttacttctt cccacactca 5220 ttaccatgta ctctgcctta tctcccccca gagtttgatg ctccaagccc tctcccagag 5280 actacagaga acgtggtgtg tgccctgggc ctgactgtgg gtctggtggg catcattatt 5340 gggaccatct tcatcatcaa gggagtgcgc aaaagcaatg cagcagaacg cagggggcct 5400 ctgtaaggca catggaggtg agttaggtgt ggtcagagga agacatatat ggagatatct 5460 gagggaggaa aacagggtgg ggaaaggaaa tgtaatgcat ttaagagaca aggtaggaac 5520 agatgtggct cttgatttct ctttgctaga atgaatcaga cattggtatc atctggtatc 5580 ccaaagcttc agggtctgtc atccctttct atagacgggc accttgatca cggctccagt 5640 cttagaaatc atctccagta cctaaaacca ttgtttcaca ttagaatact gagtctaggg 5700 atctagaaaa tacattagaa tatggagtct agggatctag aaaatactga gtctagggat 5760 ctagaaaaat aagcctcaag atttgggcac atcctagctt gtatttcctg gggcaggtca 5820 tcagttcaga agcatttcca gatcctggct cctttcaggt tagggtcaat tcattgcatg 5880 aaatgggaat ctcttagagg ccaatgcctg cttttgcttc tttagtctca aatgtagtat 5940 gagaaactct aaaaaaaggt aaagcatggt tgcttattat gttcagttgg agagtaggaa 6000 ctaactgtat acagttagtt catgttggaa aggttagatg aacattgaaa gaattttgca 6060 aagtcaaagg attaagagag aagaggaagg aatctgaagc aaggagctca aaacggatct 6120 taaattcctt ggtaactatg tgtgtcttgc tataggtgat ggtgtttctt agagagaaga 6180 tcactgaaga aacttctgct ttaatgactt tacaaagctg gcaatattac aatccttgac 6240 ctcagtgaaa gcagtcatct tcagcgtttt ccagccctat agccacccca agtgtggtta 6300 tgcctcctcg attgctccgt actctaacat ctagctggct tccctgtcta ttgccttttc 6360 ctgtatctat tttcctctat ttcctatcat tttattatca ccatgcaatg cctctggaat 6420 aaaacataca ggagtctgtc tctgctatgg aatgccccat ggggcatctc ttgtgtactt 6480 attgtttaag gtttcctcaa actgtgattt ttctgaacac aataaactat tttgatgatc 6540 ttgggtggaa tttttggtgt ttaagccagt tctttgggtg gcggtggggg gtggggagtc 6600 ggtcctgggg aatatatgtg atcctttccc ggtaaaatat ctgaatgttg aatttatctt 6660 ataaattcta gaattcatca gacatatccc ggttcatttg ggcttggtct cattttgtgc 6720 atctgcaggc aaccctcttg ttgtggtcta gtcctcatca ggaaaaccta aagtggggtt 6780 ggtttgttgg gagatctcta ctgagcaatg atataactct gtcttcagta gagtgaatct 6840 gaaaccccaa ggtatggatc tcagaatgca tgggatagag gggagcagat ggggttagag 6900 tggggagaag gaagacagaa gaatccataa acattgcagg atttacatat caacatcgtt 6960 cattccagat ttaatgagca aagaggttgg acactgaaga ctggccttac ccattctgtt 7020 agacatagtc tcagatgcct attttattac cgagagagta gtctgactga ttcttgaaac 7080 caccttatat ttgaagatgt gtctttgagt ggaaaagctg agtgaaattt ggggttgggg 7140 agaaagatat gacattaaga tgagaggaag gaatatttga aacacaatga actgttgctc 7200 atttgtctat aaaactatga cttgatattt atctctaaaa tagtttctag aacctgccat 7260 aaaccactaa gataaactat tcatgatagt gtggtagact gcaaataaat gctgttgaaa 7320 tgagttaggc ttgggtttca tcttggctgt atcatttact agctatgttt tcactggtat 7380 cttacttaac ttagcctcac attactcatg aaaatactgg tgttaatttt tactacattg 7440 aattaatatc agaattaaaa ggaaaacgca agcaaagtaa ttagatacat gcttagtgat 7500 aataaaatat tgcaaaaaat tatacattct gttgtttttc tcaaaatttc tatagactga 7560 tgataaaaat ctaagagaag ctaaacaaaa caaggataaa ccaaagcatc atgacattct 7620 aagccttact aataaataag aagtttctcg gctgggcacg gtggctcacg cctgtaatcc 7680 agcactttgg gaggccgagg tgggcggatc acaaggtcag gaaatcaaga ccatcctggc 7740 caacatggtg aaaccccatc tctactaaaa atacaaaaat tagccaggcg tggtgatagg 7800 cgcctgtaat cccagctact ctggaggttg aggcaggaga atctcttgaa tccgggaggc 7860 agaggttgca gtgagccgag atcgcaccac tgcgctcctg cctggcaaca gactgagact 7920 ccgtctcaaa aaaaaaaaaa aaaaaaaagt ttctctactg ttggttcaga gaatcaaagc 7980 agaatcttga gactactgat ggtagaatag gtacgagtgt ctttcttaca tgactacaaa 8040 ctttattata aaataaatag cttaacacag agaatacact aaaacttaga caagcatgga 8100 ttaagaaagc aaaaagtaaa cccatatact accatgtaag aaaaccattt ttggccaggt 8160 gcggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 8220 tcaggagatc gagaccatcc tggctaacat ggtgaaaccc cgtctctact aaaaaaaaac 8280 aaaacaaaaa attagccggg tgtggtggcg ggtgcctgta gtcccagcta ctcgagaagt 8340 tgaggcagga aaatggcgtg aacccaagag gcagagcttg cagtaagccg agatcacacc 8400 actgcactcc agcctgggcg acagagcgag actccatctc aaaaaaaaga aaaaaaaaaa 8460 aaaaaaaaaa aaaaaggaaa accattttaa tagactttta tttttagagc tgttttaagc 8520 taacagaaaa attgcagaaa ttgtatacag agctccccca cccccagttt ctacaatgct 8580 taacatcctg tattaatgtg gtacacttgt tacaattgat gaaccaatac taataattat 8640 tattaactaa aattcatagt tatacgaggg ttcactctgt atta 8684 // ID OX111332; SV 1; linear; genomic DNA; STD; HUM; 8684 BP. XX AC OX111332; XX PR Project:PRJEB53805; XX DT 07-JUL-2022 (Rel. 144, Created) DT 05-AUG-2022 (Rel. 144, Last updated, Version 2) XX DE Homo sapiens HLA-DRA gene for MHC class II antigen, allele DE HLA-DRA*01:01:01:NEW XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Turner R T.; RT ; RL Submitted (23-JUN-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, The Royal Free Hospital, Pond Street, RL London, NW3 2QU, United Kingdom XX DR MD5; ac140ff3912cde1ecdba70eb60ba5fd9. XX FH Key Location/Qualifiers FH FT source 1..8684 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="AN301110" FT /db_xref="taxon:9606" FT CDS join(1449..1530,3944..4189,4681..4962,5252..5406) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH8161938.1" FT /translation="MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSG FT EFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNY FT TPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFL FT PREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL FT GLTVGLVGIIIGTIFIIKGVRKSNAAERRGPL" FT exon 1449..1530 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=1 FT intron 1531..3943 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=1 FT exon 3944..4189 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=2 FT intron 4190..4680 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=2 FT exon 4681..4962 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=3 FT intron 4963..5251 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=3 FT exon 5252..5406 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=4 XX SQ Sequence 8684 BP; 2536 A; 1810 C; 1847 G; 2491 T; 0 other; ctccctcact gccaggtcac tcttcatgga agtatttgta ttccagtcct ttctgtggaa 60 agaaattaac attctccttt tcataacact gtatcttcag aaacaagaga gtcgaagtct 120 cctaattttc aggactgtct atgttgaaca tcaaaatata ttctttagag cagatcttta 180 ataatcatat gacaagagaa aaactttcat aatcttatga catgagggaa ggaatattaa 240 agccgttctg tgggttatta tctctaacgt tcccaataga ataggctttg ccagctgggt 300 gcggtggctc atgcctgtaa tcccagcact ttgcgaggcc aaggcgggca aatcacgagg 360 tcaggagtct gagaccagcc tgaccaacat ggtgaaaccc cgtctctact aaaaatacaa 420 aaattagccg ggcatggtgg tgggcgcctg taatcccagc tactcaggag gctgaggcag 480 gagaatcgct tgaacccggg aggcggagat tacaatgagc tgagatcaca ccaccaactc 540 cagcttgggc gacagagcaa gactctgtct aaaaaaaaaa aaaaaaaaaa agaataggct 600 ttgcccacta tactctctca tattcattga cctgaatcct caaatgaggt gtgtccatta 660 gtcaactcca atctcttgtc atatataaga tggtagagat gagaagaagg tagctccttt 720 acagcccact atttccacta actactacct gtgtttcaag atacagcctt tcatccttct 780 ccagtgttga gagtgttgaa cctcagagtt tctcctctca ttttctctaa atgagataca 840 atgccagcca tcccaagctc ttggcctgag ttgatcatct tgaagtctag gactccaaga 900 agcatgaaag agcttcttta gtgaagctat gtcctcagta ctgccaaaat tcagacaatc 960 tccatggcct gacaatttac cttctatttg ggtaatttat tgtcccttac gcaaactctc 1020 caactgtcat tgcacagaca tatgatctgt atttagctct cactttaggt gtttccattg 1080 attctattct cactaatgtg cttcaggtat atccctgtct agaagtcaga ttggggttaa 1140 agagtctgtc cgtgattgac taacagtctt aaatacttga tttgttgttg ttgttgtcct 1200 gtttgtttaa gaactttact tctttatcca atgaacggag tatcttgtgt cctggaccct 1260 ttgcaagaac ccttccccta gcaacagatg cgtcatctca aaatattttt ctgattggcc 1320 aaagagtaat tgatttgcat tttaatggtc agactctatt acaccccaca ttctcttttc 1380 ttttattctt gtctgttctg cctcactccc gagctctact gactcccaaa agagcgccca 1440 agaagaaaat ggccataagt ggagtccctg tgctaggatt tttcatcata gctgtgctga 1500 tgagcgctca ggaatcatgg gctatcaaag gtaggtgctg agggaatgaa atctgggacg 1560 atagactacg aagcattgga gaaaagacct atggacattt ggaagataat gtgtggagtg 1620 aaagaatagt gtgacaggta ttatgtggtc tcgacagaaa gtataacaaa ttgtggtttg 1680 gtggagttct tccctcacca caaactgaag taagtcaaat ttggtttaga gggtcaaaac 1740 tgagttgtgt attgatgaat agcacggtcc tgctacaagc caaactgggg gtgggggtgg 1800 gggtggggga ggaagaatat tttctggcaa gcattaacaa gttatatttc tgggctttaa 1860 ttattctttc tggaaaatta gtaaaattaa aaactaaaaa ccacacatag ttttgctaga 1920 attaaatgaa aaaaaaagtt attagccctg ttcttatctg aatacatgat acagtagtta 1980 ttttttggag tgtaaatcct gtcggtatat attgagcaca tatattgtgt tgaagattac 2040 tagaaggaaa agtcatcaaa aagcaacaat ttaccccagg aaaaggggag ggaaggcatg 2100 ctgatatgag ttgcctcatg ggacagtgat agccattccc tgccttccca tctccatggt 2160 acagcagatc ttatatcatg ttaacttagt aatatttcca agagagtaga aaaataagga 2220 aggaaatggg gaatctgata ttattctctc tcatctccag agcaacattg gtgctgttgt 2280 aaagatgtac tgtagaaaag tattcttcac ccagcgtgac ccccacagaa ggtgtcaggt 2340 agacttgaaa taagcaaagt aataacccag ctcccatacc catagtggca attgtagatt 2400 tctattgccc caaaagagcc atacataggg atacttacct agaaagacag aggctcttcc 2460 cttggtttgt gaagaggcag ctagtatatt tgtgtgtgtt tgcatagatg caaacggtaa 2520 ataaattcct aggtttatca atacacagtc aaacattaaa atctctcatc ttggctgggc 2580 acggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 2640 tcaagagatc gagaccgtcc tgggcaacat ggtgaaaccc cgtctctact aaaaatacaa 2700 aaaattagct gggtatggtg gcacacgcct gtagtcccag ctactcggga ggctgaggca 2760 ggaggattgc ttgagcccgg gaggcggagg ttgcagtgag ctgagatggt gccactgcac 2820 tccagcctgg cgatagagca agactccgtc tcaaacaacc aaaccaaaac aaaacaaaat 2880 atctcacctt atctttgaag actaaggaaa aaaaaaatct cccactcatc gatacactcc 2940 acagaggcag catactctcc cagtgtagct ttctcttttc atgttcatta ttcccttggt 3000 gttggttatt ctcaatgtca atcgtaacag aacatcttcc ataataacag tcccaattta 3060 aggagcatta agataaaagg tggaattgcc aaggtcaatc cagacgagaa ccttctcata 3120 gaggtaacca ccgtgtgggt ttggatgctg ggaagcaggg ggactatgac gctacaaggt 3180 ctcagtctta atttttggag tacttcagtc cccaggtata ttttccatag atttggccct 3240 taaataaaaa gaagcttctg actctaaaat gtaaacagtg cttgttacag tcttgttgat 3300 atattaagaa attactcacc ttatctcatt taatcttaaa aacaaacccc tgacaggatc 3360 aaaaccacag cagggctaca taataggaaa actatacata aataggtaga ataatctgct 3420 caggatcact aggtaagttg ctgaataaga attcaagatg tttttgatcc cagagtttaa 3480 aacccaacct ttcaaacagt gtttccttct tcttagagta caatgttctg agaaagagat 3540 cctctggaat tctggcctaa gtgtatttaa tgcccgggta aagaaagtga gagaacattt 3600 ctctttaggg gctgctgctg gatttctaaa aagaaaataa tttctcagct agtaacatgg 3660 agccaaacaa cagcttcaca agactctggg ttctttagcc ctcatctcct tcaatccacc 3720 ctctttataa ccagtccttc ttgtttttcc cctcccagct ttgttcagca gcatgccctt 3780 cacccagacc ttgtcttgtc actcatccct actcgccatc attctttcat tcctcttggc 3840 ccaatctctc tccaccactt cctgcctaca tgtatgtagg ttattcattt ccctctcttg 3900 attcccccca cccaactctc tttctccatt tcttgccttt cagaagaaca tgtgatcatc 3960 caggccgagt tctatctgaa tcctgaccaa tcaggcgagt ttatgtttga ctttgatggt 4020 gatgagattt tccatgtgga tatggcaaag aaggagacgg tctggcggct tgaagaattt 4080 ggacgatttg ccagctttga ggctcaaggt gcattggcca acatagctgt ggacaaagcc 4140 aacctggaaa tcatgacaaa gcgctccaac tatactccga tcaccaatgg tacctccctc 4200 tctgctgcac tcctggacat gggaatccat agtttgaaag tagttgcttc agctctttgt 4260 gttagattat tgtaactgat tttccctcca agggcctaac cttgccatta acaagcccca 4320 aattctcatg ccagaggtct gagaacttta tgggtttgat cctatcttgt tgtgctcaag 4380 tcttgtctct gtcatccatg gtctcctacg aagtcattgc cctaagttca tgctagggga 4440 gccagaaggg aagtccttgg atatcttata cctcaatatt ggctcaattt cttggggagg 4500 gggtgctgtc agagattgtt atctgaggat gtgacataga tttctcaggg cacaatttca 4560 actacttttt cagctttagg gtttttagat acgtttgtac cacaattgag catgggaggg 4620 agaggggtga gcctaagcag tgatggctga tttctgtcac gtctgtcatg tgtcccccag 4680 tacctccaga ggtaactgtg ctcacgaaca gccctgtgga actgagagag cccaacgtcc 4740 tcatctgttt catcgacaag ttcaccccac cagtggtcaa tgtcacgtgg cttcgaaatg 4800 gaaaacctgt caccacagga gtgtcagaga cagtcttcct gcccagggaa gaccaccttt 4860 tccgcaagtt ccactatctc cccttcctgc cctcaactga ggacgtttac gactgcaggg 4920 tggagcactg gggcttggat gagcctcttc tcaagcactg gggtatggac caacactcaa 4980 tctcctttat ttcaaggttt cctcctatga tgcttgtgtg aaactcggtg ttctaactgt 5040 ttcataatat ctgctacaat taatataact gtcttctcct actatccagc ttcctccttt 5100 ttttaatctg taattctctc aatacatcat tctgtcttcc tcttctttaa tctatgaata 5160 acttttctct ttattaagaa ccctacattt gattctgagt gttacttctt cccacactca 5220 ttaccatgta ctctgcctta tctcccccca gagtttgatg ctccaagccc tctcccagag 5280 actacagaga acgtggtgtg tgccctgggc ctgactgtgg gtctggtggg catcattatt 5340 gggaccatct tcatcatcaa gggagtgcgc aaaagcaatg cagcagaacg cagggggcct 5400 ctgtaaggca catggaggtg agttaggtgt ggtcagagga agacatatat ggagatatct 5460 gagggaggaa aacagggtgg ggaaaggaaa tgtaatgcat ttaagagaca aggtaggaac 5520 agatgtggct cttgatttct ctttgctaga atgaatcaga cattggtatc atctggtatc 5580 ccaaagcttc agggtctgtc atccctttct atagacgggc accttgatca cggctccagt 5640 cttagaaatc atctccagta cctaaaacca ttgtttcaca ttagaatact gagtctaggg 5700 atctagaaaa tacattagaa tatggagtct agggatctag aaaatactga gtctagggat 5760 ctagaaaaat aagcctcaag atttgggcac atcctagctt gtatttcctg gggcaggtca 5820 tcagttcaga agcatttcca gatcctggct cctttcaggt tagggtcaat tcattgcatg 5880 aaatgggaat ctcttagagg ccaatgcctg cttttgcttc tttagtctca aatgtagtat 5940 gagaaactct aaaaaaaggt aaagcatggt tgcttattat gttcagttgg agagtaggaa 6000 ctaactgtat acagttagtt catgttggaa aggttagatg aacattgaaa gaattttgca 6060 aagtcaaagg attaagagag aagaggaagg aatctgaagc aaggagctca aaacggatct 6120 taaattcctt ggtaactatg tgtgtcttgc tataggtgat ggtgtttctt agagagaaga 6180 tcactgaaga aacttctgct ttaatgactt tacaaagctg gcaatattac aatccttgac 6240 ctcagtgaaa gcagtcatct tcagcgtttt ccagccctat agccacccca agtgtggtta 6300 tgcctcctcg attgctccgt actctaacat ctagctggct tccctgtcta ttgccttttc 6360 ctgtatctat tttcctctat ttcctatcat tttattatca ccatgcaatg cctctggaat 6420 aaaacataca ggagtctgtc tctgctatgg aatgccccat ggggcatctc ttgtgtactt 6480 attgtttaag gtttcctcaa actgtgattt ttctgaacac aataaactat tttgatgatc 6540 ttgggtggaa tttttggtgt ttaagccagt tctttgggtg gcggtggggg gtggggagtc 6600 ggtcctgggg aatatatgtg atcctttccc ggtaaaatat ctgaatgttg aatttatctt 6660 ataaattcta gaattcatca gacatatccc ggttcatttg ggcttggtct cattttgtgc 6720 atctgcaggc aaccctcttg ttgtggtcta gtcctcatca ggaaaaccta aagtggggtt 6780 ggtttgttgg gagatctcta ctgagcaatg atataactct gtcttcagta gagtgaatct 6840 gaaaccccaa ggtatggatc tcagaatgca tgggatagag gggagcagat ggggttagag 6900 tggggagaag gaagacagaa gaatccataa acattgcagg atttacatat caacatcgtt 6960 cattccagat ttaatgagca aagaggttgg acactgaaga ctggccttac ccattctgtt 7020 agacatagtc tcagatgcct attttattac cgagagagta gtctgactga ttcttgaaac 7080 caccttatat ttgaagatgt gtctttgagt ggaaaagctg agtgaaattt ggggttgggg 7140 agaaagatat gacattaaga tgagaggaag gaatatttga aacacaatga actgttgctc 7200 atttgtctat aaaactatga cttgatattt atctctaaaa tagtttctag aacctgccat 7260 aaaccactaa gataaactat tcatgatagt gtggtagact gcaaataaat gctgttgaaa 7320 tgagttaggc ttgggtttca tcttggctgt atcatttact agctatgttt tcactggtat 7380 cttacttaac ttagcctcac attactcatg aaaatactgg tgttaatttt tactacattg 7440 aattaatatc agaattaaaa ggaaaacgca agcaaagtaa ttagatacat gcttagtgat 7500 aataaaatat tgcaaaaaat tatacattct gttgtttttc tcaaaatttc tatagactga 7560 tgataaaaat ctaagagaag ctaaacaaaa caaggataaa ccaaagcatc atgacattct 7620 aagccttact aataaataag aagtttctcg gctgggcacg gtggctcacg cctgtaatcc 7680 agcactttgg gaggccgagg tgggcggatc acaaggtcag gaaatcaaga ccatcctggc 7740 caacatggtg aaaccccatc tctactaaaa atacaaaaat tagccaggcg tggtgatagg 7800 cgcctgtaat cccagctact ctggaggttg aggcaggaga atctcttgaa tccgggaggc 7860 agaggttgca gtgagccgag atcgcaccac tgcgctcctg cctggcaaca gactgagact 7920 ccgtctcaaa aaaaaaaaaa aaaaaaaagt ttctctactg ttggttcaga gaatcaaagc 7980 agaatcttga gactactgat ggtagaatag gtacgagtgt ctttcttaca tgactacaaa 8040 ctttattata aaataaatag cttaacacag agaatacact aaaacttaga caagcatgga 8100 ttaagaaagc aaaaagtaaa cccatatact accatgtaag aaaaccattt ttggccaggt 8160 gcggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 8220 tcaggagatc gagaccatcc tggctaacat ggtgaaaccc cgtctctact aaaaaaaaac 8280 aaaacaaaaa attagccggg tgtggtggcg ggtgcctgta gtcccagcta ctcgagaagt 8340 tgaggcagga aaatggcgtg aacccaagag gcagagcttg cagtaagccg agatcacacc 8400 actgcactcc agcctgggcg acagagcgag actccatctc aaaaaaaaga aaaaaaaaaa 8460 aaaaaaaaaa aaaaaggaaa accattttaa tagactttta tttttagagc tgttttaagc 8520 taacagaaaa attgcagaaa ttgtatacag agctccccca cccccagttt ctacaatgct 8580 taacatcctg tattaatgtg gtacacttgt tacaattgat gaaccaatac taataattat 8640 tattaactaa aattcatagt tatacgaggg ttcactctgt atta 8684 // ID OX111333; SV 1; linear; genomic DNA; STD; HUM; 8684 BP. XX AC OX111333; XX PR Project:PRJEB53805; XX DT 07-JUL-2022 (Rel. 144, Created) DT 05-AUG-2022 (Rel. 144, Last updated, Version 2) XX DE Homo sapiens HLA-DRA gene for MHC class II antigen, allele DE HLA-DRA*01:01:01:NEW XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. XX RN [1] RA Turner R T.; RT ; RL Submitted (23-JUN-2022) to the INSDC. RL ANTHONY NOLAN RESEARCH INSTITUTE, The Royal Free Hospital, Pond Street, RL London, NW3 2QU, United Kingdom XX DR MD5; ac140ff3912cde1ecdba70eb60ba5fd9. XX FH Key Location/Qualifiers FH FT source 1..8684 FT /organism="Homo sapiens" FT /mol_type="genomic DNA" FT /clone="AN301111" FT /db_xref="taxon:9606" FT CDS join(1449..1530,3944..4189,4681..4962,5252..5406) FT /codon_start=1 FT /transl_table=1 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /product="MHC class II antigen" FT /function="antigen presenting molecule" FT /protein_id="CAH8161939.1" FT /translation="MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSG FT EFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNY FT TPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFL FT PREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL FT GLTVGLVGIIIGTIFIIKGVRKSNAAERRGPL" FT exon 1449..1530 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=1 FT intron 1531..3943 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=1 FT exon 3944..4189 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=2 FT intron 4190..4680 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=2 FT exon 4681..4962 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=3 FT intron 4963..5251 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=3 FT exon 5252..5406 FT /gene="HLA-DRA" FT /allele="HLA-DRA*01:01:01:NEW" FT /number=4 XX SQ Sequence 8684 BP; 2536 A; 1810 C; 1847 G; 2491 T; 0 other; ctccctcact gccaggtcac tcttcatgga agtatttgta ttccagtcct ttctgtggaa 60 agaaattaac attctccttt tcataacact gtatcttcag aaacaagaga gtcgaagtct 120 cctaattttc aggactgtct atgttgaaca tcaaaatata ttctttagag cagatcttta 180 ataatcatat gacaagagaa aaactttcat aatcttatga catgagggaa ggaatattaa 240 agccgttctg tgggttatta tctctaacgt tcccaataga ataggctttg ccagctgggt 300 gcggtggctc atgcctgtaa tcccagcact ttgcgaggcc aaggcgggca aatcacgagg 360 tcaggagtct gagaccagcc tgaccaacat ggtgaaaccc cgtctctact aaaaatacaa 420 aaattagccg ggcatggtgg tgggcgcctg taatcccagc tactcaggag gctgaggcag 480 gagaatcgct tgaacccggg aggcggagat tacaatgagc tgagatcaca ccaccaactc 540 cagcttgggc gacagagcaa gactctgtct aaaaaaaaaa aaaaaaaaaa agaataggct 600 ttgcccacta tactctctca tattcattga cctgaatcct caaatgaggt gtgtccatta 660 gtcaactcca atctcttgtc atatataaga tggtagagat gagaagaagg tagctccttt 720 acagcccact atttccacta actactacct gtgtttcaag atacagcctt tcatccttct 780 ccagtgttga gagtgttgaa cctcagagtt tctcctctca ttttctctaa atgagataca 840 atgccagcca tcccaagctc ttggcctgag ttgatcatct tgaagtctag gactccaaga 900 agcatgaaag agcttcttta gtgaagctat gtcctcagta ctgccaaaat tcagacaatc 960 tccatggcct gacaatttac cttctatttg ggtaatttat tgtcccttac gcaaactctc 1020 caactgtcat tgcacagaca tatgatctgt atttagctct cactttaggt gtttccattg 1080 attctattct cactaatgtg cttcaggtat atccctgtct agaagtcaga ttggggttaa 1140 agagtctgtc cgtgattgac taacagtctt aaatacttga tttgttgttg ttgttgtcct 1200 gtttgtttaa gaactttact tctttatcca atgaacggag tatcttgtgt cctggaccct 1260 ttgcaagaac ccttccccta gcaacagatg cgtcatctca aaatattttt ctgattggcc 1320 aaagagtaat tgatttgcat tttaatggtc agactctatt acaccccaca ttctcttttc 1380 ttttattctt gtctgttctg cctcactccc gagctctact gactcccaaa agagcgccca 1440 agaagaaaat ggccataagt ggagtccctg tgctaggatt tttcatcata gctgtgctga 1500 tgagcgctca ggaatcatgg gctatcaaag gtaggtgctg agggaatgaa atctgggacg 1560 atagactacg aagcattgga gaaaagacct atggacattt ggaagataat gtgtggagtg 1620 aaagaatagt gtgacaggta ttatgtggtc tcgacagaaa gtataacaaa ttgtggtttg 1680 gtggagttct tccctcacca caaactgaag taagtcaaat ttggtttaga gggtcaaaac 1740 tgagttgtgt attgatgaat agcacggtcc tgctacaagc caaactgggg gtgggggtgg 1800 gggtggggga ggaagaatat tttctggcaa gcattaacaa gttatatttc tgggctttaa 1860 ttattctttc tggaaaatta gtaaaattaa aaactaaaaa ccacacatag ttttgctaga 1920 attaaatgaa aaaaaaagtt attagccctg ttcttatctg aatacatgat acagtagtta 1980 ttttttggag tgtaaatcct gtcggtatat attgagcaca tatattgtgt tgaagattac 2040 tagaaggaaa agtcatcaaa aagcaacaat ttaccccagg aaaaggggag ggaaggcatg 2100 ctgatatgag ttgcctcatg ggacagtgat agccattccc tgccttccca tctccatggt 2160 acagcagatc ttatatcatg ttaacttagt aatatttcca agagagtaga aaaataagga 2220 aggaaatggg gaatctgata ttattctctc tcatctccag agcaacattg gtgctgttgt 2280 aaagatgtac tgtagaaaag tattcttcac ccagcgtgac ccccacagaa ggtgtcaggt 2340 agacttgaaa taagcaaagt aataacccag ctcccatacc catagtggca attgtagatt 2400 tctattgccc caaaagagcc atacataggg atacttacct agaaagacag aggctcttcc 2460 cttggtttgt gaagaggcag ctagtatatt tgtgtgtgtt tgcatagatg caaacggtaa 2520 ataaattcct aggtttatca atacacagtc aaacattaaa atctctcatc ttggctgggc 2580 acggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 2640 tcaagagatc gagaccgtcc tgggcaacat ggtgaaaccc cgtctctact aaaaatacaa 2700 aaaattagct gggtatggtg gcacacgcct gtagtcccag ctactcggga ggctgaggca 2760 ggaggattgc ttgagcccgg gaggcggagg ttgcagtgag ctgagatggt gccactgcac 2820 tccagcctgg cgatagagca agactccgtc tcaaacaacc aaaccaaaac aaaacaaaat 2880 atctcacctt atctttgaag actaaggaaa aaaaaaatct cccactcatc gatacactcc 2940 acagaggcag catactctcc cagtgtagct ttctcttttc atgttcatta ttcccttggt 3000 gttggttatt ctcaatgtca atcgtaacag aacatcttcc ataataacag tcccaattta 3060 aggagcatta agataaaagg tggaattgcc aaggtcaatc cagacgagaa ccttctcata 3120 gaggtaacca ccgtgtgggt ttggatgctg ggaagcaggg ggactatgac gctacaaggt 3180 ctcagtctta atttttggag tacttcagtc cccaggtata ttttccatag atttggccct 3240 taaataaaaa gaagcttctg actctaaaat gtaaacagtg cttgttacag tcttgttgat 3300 atattaagaa attactcacc ttatctcatt taatcttaaa aacaaacccc tgacaggatc 3360 aaaaccacag cagggctaca taataggaaa actatacata aataggtaga ataatctgct 3420 caggatcact aggtaagttg ctgaataaga attcaagatg tttttgatcc cagagtttaa 3480 aacccaacct ttcaaacagt gtttccttct tcttagagta caatgttctg agaaagagat 3540 cctctggaat tctggcctaa gtgtatttaa tgcccgggta aagaaagtga gagaacattt 3600 ctctttaggg gctgctgctg gatttctaaa aagaaaataa tttctcagct agtaacatgg 3660 agccaaacaa cagcttcaca agactctggg ttctttagcc ctcatctcct tcaatccacc 3720 ctctttataa ccagtccttc ttgtttttcc cctcccagct ttgttcagca gcatgccctt 3780 cacccagacc ttgtcttgtc actcatccct actcgccatc attctttcat tcctcttggc 3840 ccaatctctc tccaccactt cctgcctaca tgtatgtagg ttattcattt ccctctcttg 3900 attcccccca cccaactctc tttctccatt tcttgccttt cagaagaaca tgtgatcatc 3960 caggccgagt tctatctgaa tcctgaccaa tcaggcgagt ttatgtttga ctttgatggt 4020 gatgagattt tccatgtgga tatggcaaag aaggagacgg tctggcggct tgaagaattt 4080 ggacgatttg ccagctttga ggctcaaggt gcattggcca acatagctgt ggacaaagcc 4140 aacctggaaa tcatgacaaa gcgctccaac tatactccga tcaccaatgg tacctccctc 4200 tctgctgcac tcctggacat gggaatccat agtttgaaag tagttgcttc agctctttgt 4260 gttagattat tgtaactgat tttccctcca agggcctaac cttgccatta acaagcccca 4320 aattctcatg ccagaggtct gagaacttta tgggtttgat cctatcttgt tgtgctcaag 4380 tcttgtctct gtcatccatg gtctcctacg aagtcattgc cctaagttca tgctagggga 4440 gccagaaggg aagtccttgg atatcttata cctcaatatt ggctcaattt cttggggagg 4500 gggtgctgtc agagattgtt atctgaggat gtgacataga tttctcaggg cacaatttca 4560 actacttttt cagctttagg gtttttagat acgtttgtac cacaattgag catgggaggg 4620 agaggggtga gcctaagcag tgatggctga tttctgtcac gtctgtcatg tgtcccccag 4680 tacctccaga ggtaactgtg ctcacgaaca gccctgtgga actgagagag cccaacgtcc 4740 tcatctgttt catcgacaag ttcaccccac cagtggtcaa tgtcacgtgg cttcgaaatg 4800 gaaaacctgt caccacagga gtgtcagaga cagtcttcct gcccagggaa gaccaccttt 4860 tccgcaagtt ccactatctc cccttcctgc cctcaactga ggacgtttac gactgcaggg 4920 tggagcactg gggcttggat gagcctcttc tcaagcactg gggtatggac caacactcaa 4980 tctcctttat ttcaaggttt cctcctatga tgcttgtgtg aaactcggtg ttctaactgt 5040 ttcataatat ctgctacaat taatataact gtcttctcct actatccagc ttcctccttt 5100 ttttaatctg taattctctc aatacatcat tctgtcttcc tcttctttaa tctatgaata 5160 acttttctct ttattaagaa ccctacattt gattctgagt gttacttctt cccacactca 5220 ttaccatgta ctctgcctta tctcccccca gagtttgatg ctccaagccc tctcccagag 5280 actacagaga acgtggtgtg tgccctgggc ctgactgtgg gtctggtggg catcattatt 5340 gggaccatct tcatcatcaa gggagtgcgc aaaagcaatg cagcagaacg cagggggcct 5400 ctgtaaggca catggaggtg agttaggtgt ggtcagagga agacatatat ggagatatct 5460 gagggaggaa aacagggtgg ggaaaggaaa tgtaatgcat ttaagagaca aggtaggaac 5520 agatgtggct cttgatttct ctttgctaga atgaatcaga cattggtatc atctggtatc 5580 ccaaagcttc agggtctgtc atccctttct atagacgggc accttgatca cggctccagt 5640 cttagaaatc atctccagta cctaaaacca ttgtttcaca ttagaatact gagtctaggg 5700 atctagaaaa tacattagaa tatggagtct agggatctag aaaatactga gtctagggat 5760 ctagaaaaat aagcctcaag atttgggcac atcctagctt gtatttcctg gggcaggtca 5820 tcagttcaga agcatttcca gatcctggct cctttcaggt tagggtcaat tcattgcatg 5880 aaatgggaat ctcttagagg ccaatgcctg cttttgcttc tttagtctca aatgtagtat 5940 gagaaactct aaaaaaaggt aaagcatggt tgcttattat gttcagttgg agagtaggaa 6000 ctaactgtat acagttagtt catgttggaa aggttagatg aacattgaaa gaattttgca 6060 aagtcaaagg attaagagag aagaggaagg aatctgaagc aaggagctca aaacggatct 6120 taaattcctt ggtaactatg tgtgtcttgc tataggtgat ggtgtttctt agagagaaga 6180 tcactgaaga aacttctgct ttaatgactt tacaaagctg gcaatattac aatccttgac 6240 ctcagtgaaa gcagtcatct tcagcgtttt ccagccctat agccacccca agtgtggtta 6300 tgcctcctcg attgctccgt actctaacat ctagctggct tccctgtcta ttgccttttc 6360 ctgtatctat tttcctctat ttcctatcat tttattatca ccatgcaatg cctctggaat 6420 aaaacataca ggagtctgtc tctgctatgg aatgccccat ggggcatctc ttgtgtactt 6480 attgtttaag gtttcctcaa actgtgattt ttctgaacac aataaactat tttgatgatc 6540 ttgggtggaa tttttggtgt ttaagccagt tctttgggtg gcggtggggg gtggggagtc 6600 ggtcctgggg aatatatgtg atcctttccc ggtaaaatat ctgaatgttg aatttatctt 6660 ataaattcta gaattcatca gacatatccc ggttcatttg ggcttggtct cattttgtgc 6720 atctgcaggc aaccctcttg ttgtggtcta gtcctcatca ggaaaaccta aagtggggtt 6780 ggtttgttgg gagatctcta ctgagcaatg atataactct gtcttcagta gagtgaatct 6840 gaaaccccaa ggtatggatc tcagaatgca tgggatagag gggagcagat ggggttagag 6900 tggggagaag gaagacagaa gaatccataa acattgcagg atttacatat caacatcgtt 6960 cattccagat ttaatgagca aagaggttgg acactgaaga ctggccttac ccattctgtt 7020 agacatagtc tcagatgcct attttattac cgagagagta gtctgactga ttcttgaaac 7080 caccttatat ttgaagatgt gtctttgagt ggaaaagctg agtgaaattt ggggttgggg 7140 agaaagatat gacattaaga tgagaggaag gaatatttga aacacaatga actgttgctc 7200 atttgtctat aaaactatga cttgatattt atctctaaaa tagtttctag aacctgccat 7260 aaaccactaa gataaactat tcatgatagt gtggtagact gcaaataaat gctgttgaaa 7320 tgagttaggc ttgggtttca tcttggctgt atcatttact agctatgttt tcactggtat 7380 cttacttaac ttagcctcac attactcatg aaaatactgg tgttaatttt tactacattg 7440 aattaatatc agaattaaaa ggaaaacgca agcaaagtaa ttagatacat gcttagtgat 7500 aataaaatat tgcaaaaaat tatacattct gttgtttttc tcaaaatttc tatagactga 7560 tgataaaaat ctaagagaag ctaaacaaaa caaggataaa ccaaagcatc atgacattct 7620 aagccttact aataaataag aagtttctcg gctgggcacg gtggctcacg cctgtaatcc 7680 agcactttgg gaggccgagg tgggcggatc acaaggtcag gaaatcaaga ccatcctggc 7740 caacatggtg aaaccccatc tctactaaaa atacaaaaat tagccaggcg tggtgatagg 7800 cgcctgtaat cccagctact ctggaggttg aggcaggaga atctcttgaa tccgggaggc 7860 agaggttgca gtgagccgag atcgcaccac tgcgctcctg cctggcaaca gactgagact 7920 ccgtctcaaa aaaaaaaaaa aaaaaaaagt ttctctactg ttggttcaga gaatcaaagc 7980 agaatcttga gactactgat ggtagaatag gtacgagtgt ctttcttaca tgactacaaa 8040 ctttattata aaataaatag cttaacacag agaatacact aaaacttaga caagcatgga 8100 ttaagaaagc aaaaagtaaa cccatatact accatgtaag aaaaccattt ttggccaggt 8160 gcggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcacgagg 8220 tcaggagatc gagaccatcc tggctaacat ggtgaaaccc cgtctctact aaaaaaaaac 8280 aaaacaaaaa attagccggg tgtggtggcg ggtgcctgta gtcccagcta ctcgagaagt 8340 tgaggcagga aaatggcgtg aacccaagag gcagagcttg cagtaagccg agatcacacc 8400 actgcactcc agcctgggcg acagagcgag actccatctc aaaaaaaaga aaaaaaaaaa 8460 aaaaaaaaaa aaaaaggaaa accattttaa tagactttta tttttagagc tgttttaagc 8520 taacagaaaa attgcagaaa ttgtatacag agctccccca cccccagttt ctacaatgct 8580 taacatcctg tattaatgtg gtacacttgt tacaattgat gaaccaatac taataattat 8640 tattaactaa aattcatagt tatacgaggg ttcactctgt atta 8684 //